Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322002 | 0.81 | KMT2A (0.55) | P2RX7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13333014 | 0.81 | HSD11B1 (0.76) | P2RX7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4230030 | 0.75 | ALDH1A1 (0.70) | P2RX7ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL3607807 | 0.75 | HSD11B1 (1.00) | P2RX7ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL3327631 | 0.75 | HSD11B1 (0.67) | P2RX7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21065524 | 0.75 | SMN1; SMN2 (0.79) | P2RX7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29460273 | 0.75 | SMN1; SMN2 (0.79) | P2RX7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3363337 | 0.74 | ALDH1A1 (0.83) | P2RX7ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5247667 | 0.74 | SMN1; SMN2 (0.71) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL1186765 | 0.74 | SMN1; SMN2 (0.71) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448372-B2 | Class of triaromatic compounds targeting bifunctional phosphorylation site of STAT3 and applications thereof | Shanghai Yuyao Biotech Ltd. (CN) | 2025-10-21 | — | — | US | disclosed |
| CN-112300145-B | Tri-aromatic ring compound targeting STAT3 bifunctional phosphorylation site and application thereof | 上海宇耀生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-20220274972-A1 | CLASS OF TRIAROMATIC COMPOUNDS TARGETING BIFUNCTIONAL PHOSPHORYLATION SITE OF STAT3 AND APPLICATIONS THEREOF | Shanghai Yuyao Biotech Ltd. (CN) | 2022-09-01 | — | — | US | disclosed |
| EP-4006026-A1 | CLASS OF TRIAROMATIC COMPOUNDS TARGETING BIFUNCTIONAL PHOSPHORYLATION SITE OF STAT3 AND APPLICATIONS THEREOF | Shanghai Yuyao Biotech Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
| WO-2021017880-A1 | CLASS OF TRIAROMATIC COMPOUNDS TARGETING BIFUNCTIONAL PHOSPHORYLATION SITE OF STAT3 AND APPLICATIONS THEREOF | 上海宇耀生物科技有限公司 | 2021-02-04 | — | — | WO | disclosed |
| CN-112300145-A | Three-aromatic ring compound targeting STAT3 bifunctional phosphorylation site and application thereof | 上海宇耀生物科技有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| EP-1861384-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Sterix Limited (GB) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006100502-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | STERIX LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448372-B2 | Class of triaromatic compounds targeting bifunctional phosphorylation site of STAT3 and applications thereof | STAT3, JAK2, STAT1 | P2RX7 3422/4885ALDH1A1 1654/4885KMT2A 2388/4885 |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | P2RX7 3719/4885ALDH1A1 437/4885KMT2A 3083/4885 |
| US-20220274972-A1 | CLASS OF TRIAROMATIC COMPOUNDS TARGETING BIFUNCTIONAL PHOSPHORYLATION SITE OF STAT3 AND APPLICATIONS THEREOF | STAT3, JAK2, STAT1 | P2RX7 3422/4885ALDH1A1 1654/4885KMT2A 2388/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | P2RX7 991/4885ALDH1A1 3143/4885KMT2A 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.