SCHEMBL332368

SCHEMBL332368

CC(O)Sc1cccc(SCCS)c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.35
FOLH1 Q04609 1/20 0.35
MTNR1A P48039 7/20 0.33
MTNR1B P49286 7/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
PTGS2 P35354 1/20 0.32
MAOB P27338 3/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580864 0.82 ALDH1A1 (0.46) MAOAFOLH1MTNR1AMTNR1BALDH1A1
SCHEMBL332366 0.77 MTNR1A (0.32) MTNR1AMTNR1BALDH1A1
SCHEMBL332367 0.77 ALDH1A1 (0.38) MTNR1AMTNR1BALDH1A1MAPK1CA1
SCHEMBL22606358 0.74 ALDH1A1 (0.44) MAOAMTNR1AMTNR1BALDH1A1MAPK1
SCHEMBL25196985 0.72 HTR7 (0.39) MAOAALDH1A1MAPK1PTGS2MAOB
SCHEMBL19888283 0.71 ALDH1A1 (0.39) MAOAMTNR1AMTNR1BALDH1A1MAPK1
SCHEMBL12096023 0.70 ENPP2 (0.40) MTNR1AMTNR1B
SCHEMBL8986867 0.69 TAAR1 (0.49) SLC6A4
SCHEMBL8986874 0.69 TAAR1 (0.49) SLC6A4
SCHEMBL581540 0.69 ALDH1A1 (0.35) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574342-A Benzenedimethylene diisocyanate composition, preparation method and application thereof 万华化学集团股份有限公司 2026-02-27 CN disclosed
EP-3922656-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL AND USE OF SAME MITSUI CHEMICALS INC (JP) 2026-01-14 EP disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-4620947-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL Wanhua Chemical Group Co., Ltd. (CN) 2025-09-24 EP disclosed
US-12384870-B2 Method for setting polymerization condition and method for manufacturing optical material MITSUI CHEMICALS, INC. (JP) 2025-08-12 US disclosed
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL WANHUA CHEMICAL GROUP CO., LTD. (CN) 2025-06-19 US disclosed
CN-120136740-A Isocyanate composition, modified isocyanate, polyurethane resin and optical material 万华化学集团股份有限公司 2025-06-13 CN disclosed
CN-115894296-B Isocyanate composition, modified isocyanate, polyurethane resin and optical material 万华化学集团股份有限公司 2025-04-25 CN disclosed
CN-119822999-A Benzenedimethylene diisocyanate composition, preparation method and application thereof 万华化学集团股份有限公司 2025-04-15 CN disclosed
US-20240301171-A1 NOVEL FINE HOLLOW PARTICLES COMPRISING MELAMINE-BASED RESIN KAGOSHIMA UNIVERSITY (JP) 2024-09-12 US disclosed
EP-0329386-B1 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS (JP) 1994-08-03 EP disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL PUF60, XRCC6, XRCC5 MAOA 4049/4885FOLH1 3837/4885MTNR1A 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.