Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 17/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035889 | 0.88 | CASP1 (0.60) | CASP1CASP3 | |
| SCHEMBL7893591 | 0.83 | CASP1 (0.66) | CASP1CASP3 | |
| SCHEMBL3686640 | 0.80 | CASP1 (0.74) | CASP1CASP3 | |
| SCHEMBL29802628 | 0.80 | CASP1 (0.74) | CASP1CASP3 | |
| SCHEMBL4280674 | 0.79 | CASP1 (0.67) | CASP1 | |
| SCHEMBL4280669 | 0.79 | CASP1 (0.67) | CASP1 | |
| SCHEMBL6281724 | 0.78 | CASP1 (0.59) | CASP1CASP3MEN1ALDH1A1LMNA | |
| SCHEMBL6801541 | 0.78 | CASP1 (0.59) | CASP1CASP3MEN1ALDH1A1LMNA | |
| SCHEMBL376886 | 0.76 | CASP1 (0.67) | CASP1 | |
| SCHEMBL554032 | 0.76 | CASP1 (0.67) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048693-A1 | Treatment of COPD | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2008088617-A1 | TREATMENT OF COPD | REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-07-24 | — | — | WO | disclosed |