Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280674 | 1.00 | CASP1 (0.67) | CASP1 | |
| SCHEMBL732093 | 0.92 | CASP1 (0.66) | CASP1 | |
| SCHEMBL7166866 | 0.92 | CASP1 (0.66) | CASP1 | |
| SCHEMBL8085967 | 0.92 | CASP1 (0.66) | CASP1 | |
| SCHEMBL6261373 | 0.91 | CASP1 (0.62) | CASP1 | |
| SCHEMBL28968911 | 0.91 | CASP1 (0.62) | CASP1 | |
| SCHEMBL13724740 | 0.91 | CASP1 (0.64) | CASP1 | |
| SCHEMBL19695419 | 0.91 | CASP1 (0.64) | CASP1 | |
| SCHEMBL1067460 | 0.91 | CASP1 (0.64) | CASP1 | |
| SCHEMBL376886 | 0.91 | CASP1 (0.67) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624599-B1 | Derivatives of mono (6-amino-desoxy)cyclodextrin substituted in position 6 with an alpha aminoacid group, process of their preparation and applications | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| JP-2036162-A | — | — | None | — | — | JP | disclosed |
| EP-4725560-A2 | ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2026-04-15 | — | — | EP | disclosed |
| US-12473331-B2 | Macrocyclic compounds as proteasome inhibitors | CORNELL UNIVERSITY (US) | 2025-11-18 | — | — | US | disclosed |
| WO-2025106386-A1 | A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20250152658-A1 | CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2025-05-15 | — | — | US | disclosed |
| US-20250099600-A1 | Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-03-27 | — | — | US | disclosed |
| US-12144865-B2 | Antibody drug conjugates with enzymatically cleavable groups | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-11-19 | — | — | US | disclosed |
| EP-4425181-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | Bertis Inc (KR) | 2024-09-04 | — | — | EP | disclosed |
| EP-4406606-A2 | ANTIBODY DRUG CONJUGATES (ADCS) AND ANTIBODY PRODRUG CONJUGATES (APDCS) WITH ENZYMATICALLY CLEAVABLE G | Bayer Pharma Aktiengesellschaft (DE) | 2024-07-31 | — | — | EP | disclosed |
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |
| EP-0310341-B1 | N-(L-ASPARTYL)AMINO ALCOHOL DERIVATIVES AND SWEETENER CONTAINING THE SAME | Takasago International Corporation (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| CN-1044467-A | L-aspartyl-L-Ala, Serine and glycine dipeptide ester and acid amides sweeting agent simple substance or mixture and preparation method | ZENG GUANGZHI (CN) | 1990-08-08 | — | — | CN | disclosed |
| JP-H0236162-A | N-(L-ASPARTYL)AMINOALCOHOL DERIVATIVE AND SWEETENER CONTAINING SAID DERIVATIVE | TAKASAGO INTERNATL CORP | 1990-02-06 | — | — | JP | disclosed |
| EP-0310341-A2 | N-(L-aspartyl)amino alcohol derivatives and sweetener containing the same | Takasago International Corporation (JP) | 1989-04-05 | — | — | EP | disclosed |
| EP-0279832-A1 | ENZYMATIC PROCESS | CELLTECH LIMITED (GB) | 1988-08-31 | — | — | EP | disclosed |
| CN-86104131-A | L-asparaginyl aminodipeptide sweetening agent and preparation method | — | 1988-06-22 | — | — | CN | disclosed |
| WO-1988001650-A1 | ENZYMATIC PROCESS | CELLTECH LIMITED (GB) | 1988-03-10 | — | — | WO | disclosed |
| EP-0127411-A2 | Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride | AJINOMOTO CO., INC. (JP) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473331-B2 | Macrocyclic compounds as proteasome inhibitors | PSMB5, PSMB1, PSMB3 | CASP1 1059/4885 |
| US-20250099600-A1 | Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates | KIF18B, KIF18A, KIF5B | CASP1 4106/4885 |
| US-12144865-B2 | Antibody drug conjugates with enzymatically cleavable groups | KIFC1, KIF2C, KIF5B | CASP1 1279/4885 |
| US-20250152658-A1 | CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA | IL1R1, IL1A, IL1B | CASP1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.