Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621500 | 1.00 | LMNA (0.48) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL27300436 | 1.00 | LMNA (0.48) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL27298902 | 0.86 | CYP2D6 (0.46) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL28465870 | 0.86 | LMNA (0.48) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL2212403 | 0.80 | LMNA (0.43) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL28250030 | 0.79 | SMN1; SMN2 (0.44) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL957507 | 0.78 | FDPS (0.46) | HIF1ASMN1; SMN2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL4452546 | 0.78 | LMNA (0.52) | LMNACYP2D6HIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL1486201 | 0.77 | CA12 (0.47) | CYP3A4CYP2C19ALDH1A1CYP2C9RECQL | |
| SCHEMBL5188910 | 0.76 | ALDH1A1 (0.42) | LMNACYP2D6HIF1ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407478-A1 | New cyclotetrapeptides with pro-angiogenic properties | GENETADI Biotech, S.L. (ES) | 2012-01-18 | — | — | EP | disclosed |