Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621500 | 0.86 | LMNA (0.48) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL27300436 | 0.86 | LMNA (0.48) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL332422 | 0.86 | LMNA (0.48) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL1697372 | 0.84 | ALDH1A1 (0.48) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL13071451 | 0.77 | RIPK1 (0.45) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL3482896 | 0.76 | MEN1 (0.47) | LMNASMN1; SMN2ALDH1A1KMT2ATSHR | |
| SCHEMBL7368328 | 0.76 | LMNA (0.53) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL28465870 | 0.76 | LMNA (0.48) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL28322844 | 0.75 | SMN1; SMN2 (0.43) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL8759 | 0.72 | SLC6A2 (0.56) | CYP2D6LMNAHIF1ASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036769-A | The method for preparing Cephem Derivative and intermediate thereof | EISAI CO LTD (JP) | 1989-11-01 | — | — | CN | disclosed |