SCHEMBL3324372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2465807	0.86	KMO (0.52)	KDM4EALDH1A1POLB
	SCHEMBL3330135	0.85	CFTR (0.48)	CASP1KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2466881	0.85	DHODH (0.49)	KDM4EALDH1A1ADORA3MAPTACHE
	SCHEMBL2468156	0.84	CTRC (0.51)	CASP1KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2466889	0.83	NPSR1 (0.45)	KDM4EALDH1A1HSD17B10HPGD
	SCHEMBL2464553	0.83	KMO (0.44)	MAPTACHE
	SCHEMBL2468412	0.83	DHODH (0.55)	ADORA3MAPTDHODHSCN9A
	SCHEMBL3329998	0.83	CTRC (0.54)	KDM4EALDH1A1HSD17B10HPGDMAPT
	SCHEMBL2466331	0.83	MAP2K3 (0.51)	CASP1ALDH1A1MAPTDHODH
	SCHEMBL2469999	0.83	MAP2K3 (0.51)	CASP1KDM4EALDH1A1HPGDADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.