SCHEMBL332446

SCHEMBL332446

C=C(C(=O)OCCO)C(CC1CO1)CC1CO1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.35
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12078892 0.91 ALDH1A1 (0.36) ALDH1A1TSHRTP53
SCHEMBL11310075 0.82 THRB (0.49) ALDH1A1TSHR
SCHEMBL12079105 0.78 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL10348403 0.76 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4
SCHEMBL5430136 0.75 ALDH1A1 (0.43) ALDH1A1TSHRTP53CYP3A4
SCHEMBL15771 0.73 ALDH1A1 (0.36) ALDH1A1
SCHEMBL9453047 0.72 ALDH1A1 (0.41) ALDH1A1TSHRTP53CYP3A4
SCHEMBL5094525 0.72 TSHR (0.38) ALDH1A1TSHR
Oxirane SCHEMBL3913136 0.71 ALDH1A1 (0.40) ALDH1A1TSHRTP53CYP3A4
SCHEMBL8837669 0.71 ALDH1A1 (0.81) ALDH1A1TSHRTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8012596-B2 Photochromic lens substrate TOKUYAMA CORPORATION (JP) 2011-09-06 US claimed
EP-1607418-B1 POLYMERIZATION CURABLE COMPOSITION TOKUYAMA CORP (JP) 2008-07-09 EP claimed
WO-2006135129-A1 METHOD OF PREPARING MONODISPERSE AND HIGH- BRIDGED POLYMER PLASTIC BEAD SUNJIN CHEMICAL CO., LTD. (KR) 2006-12-21 WO claimed
US-6022496-A Chromene compound TOKUYAMA CORPORATION (JP) 2000-02-08 US claimed
CN-122037193-A Cured product, optical element, optical device, and imaging device 佳能株式会社 2026-05-15 CN disclosed
US-20260110823-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND CANON KK (JP) 2026-04-23 US disclosed
US-12529822-B2 Optical element, optical apparatus, imaging apparatus, and compound CANON KABUSHIKI KAISHA (JP) 2026-01-20 US disclosed
US-12479976-B2 Cured product, optical element, optical apparatus, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2025-11-25 US disclosed
EP-3779572-B1 OPTICAL ARTICLE HOYA LENS THAILAND LTD (TH) 2025-11-19 EP disclosed
US-20250034294-A1 CURED PRODUCT, OPTICAL ELEMENT, OPTICAL APPARATUS, AND IMAGE PICKUP APPARATUS CANON KK (JP) 2025-01-30 US disclosed
US-12146011-B2 Cured product, optical element, optical apparatus, and image pickup apparatus CANON KABUSHIKI KAISHA (JP) 2024-11-19 US disclosed
EP-3591441-B1 OPTICAL ELEMENT, MATERIAL, OPTICAL DEVICE AND COMPOUND CANON KK (JP) 2024-11-06 EP disclosed
EP-0875509-A1 Chromene compound TOKUYAMA CORPORATION (JP) 1998-11-04 EP disclosed
US-5808100-A DURABILITY TOKUYAMA CORPORATION (JP) 1998-09-15 US disclosed
EP-0810210-A2 Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-03 EP disclosed
EP-0778276-A1 Photochromic chromene derivatives TOKUYAMA CORPORATION (JP) 1997-06-11 EP disclosed
US-5631382-A PHOTOCHROMIC LENSES TOKUYAMA CORPORATION (JP) 1997-05-20 US disclosed
EP-0696582-A1 Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides TOKUYAMA CORPORATION (JP) 1996-02-14 EP disclosed
EP-0629656-A2 Photochromic article NIKON CORPORATION (JP) 1994-12-21 EP disclosed
US-5246989-A PHOTOCHROMIC COMPOUND, COMPOSITION AND USE THEREOF TOKUYAMA SODA KABISHIKI KAISHA (JP) 1993-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260110823-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND RAD51, PIEZO1, ZYX ALDH1A1 1504/4885TSHR 3260/4885TP53 4641/4885
US-12529822-B2 Optical element, optical apparatus, imaging apparatus, and compound RAD51, SEM1, PSMA3 ALDH1A1 1261/4885TSHR 3808/4885TP53 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.