Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837142 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL10348413 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL332446 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL435322 | 0.76 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL15303166 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL11310075 | 0.74 | THRB (0.49) | ALDH1A1 | |
| SCHEMBL12079105 | 0.73 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL4647897 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL9149070 | 0.72 | ALDH1A1 (0.35) | ALDH1A1TP53CYP3A4HIF1A | |
| SCHEMBL12078892 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262488-B1 | REACTIVE ORGANIC FILLER AND ITS USE | Ivoclar AG (LI) | 1990-06-06 | — | — | EP | disclosed |
| EP-0262488-A1 | Reactive organic filler and its use | Ivoclar AG (LI) | 1988-04-06 | — | — | EP | disclosed |