Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821846 | 0.77 | DRD2 (0.50) | HRH3ACHECCR3MEN1KMT2A | |
| SCHEMBL311417 | 0.72 | ACHE (0.61) | HRH3ACHECCR3DRD2DRD4 | |
| SCHEMBL7238995 | 0.70 | HRH3 (0.65) | HRH3ACHECCR3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL312187 | 0.70 | ACHE (0.59) | HRH3ACHECCR3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10625447 | 0.69 | HRH3 (0.64) | HRH3ACHECCR3MEN1KMT2A | |
| SCHEMBL2822514 | 0.69 | ACHE (0.67) | HRH3ACHEKMT2ATHRB | |
| SCHEMBL13490679 | 0.68 | HRH3 (0.55) | HRH3ACHEDRD2DRD4DRD3 | |
| SCHEMBL27759412 | 0.68 | CHRM4 (0.50) | — | |
| SCHEMBL1002852 | 0.68 | MEN1 (0.81) | ACHECCR3MEN1KMT2ADRD2 | |
| SCHEMBL8844616 | 0.68 | ACHE (0.48) | HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137368-A1 | PYRIDINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137368-A1 | PYRIDINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | DRD2, GRIN2C, GRIN2A | HRH3 554/4885ACHE 214/4885CCR3 4440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.