SCHEMBL3324721

SCHEMBL3324721

O=S(=O)(O)c1ccc(N=NNc2ccccc2)c(-c2cccc3ccccc23)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.42
HIF1A Q16665 2/20 0.42
CYP2C9 P11712 2/20 0.42
TSHR P16473 1/20 0.42
PTPRA P18433 1/20 0.42
PTPRB P23467 1/20 0.42
CYP2C19 P33261 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SNCA P37840 1/20 0.41
PTPN11 Q06124 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
THRB P10828 2/20 0.40
MAPK1 P28482 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
SENP3 Q9H4L4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11200836 0.77 MEN1 (0.46) CYP1A2HIF1ATSHRSNCAPTPN11
SCHEMBL3324095 0.75 CYP1A1 (0.39) CYP1A2TSHRCYP2C19HSD17B10ALDH1A1
SCHEMBL6882888 0.72 CA12 (0.52) CYP1A2HIF1ACYP2C9TSHRPTPRA
SCHEMBL22062156 0.72 KMT2A (0.60) TSHRHSD17B10SNCAALDH1A1KMT2A
SCHEMBL9463211 0.71 CYP1A2 (0.47) CYP1A2HIF1ACYP2C9TSHRPTPRA
SCHEMBL8520861 0.70 TDP1 (0.52) CYP1A2CYP2C9TSHRCYP2C19HSD17B10
SCHEMBL8520862 0.70 TDP1 (0.52) CYP1A2CYP2C9TSHRCYP2C19HSD17B10
SCHEMBL2777355 0.70 MEN1 (0.72) TSHRSNCAALDH1A1KMT2AMEN1
SCHEMBL29889996 0.69 CASP6 (0.58) CYP1A2HIF1ACYP2C9TSHRPTPRA
SCHEMBL3860682 0.69 MEN1 (0.70) TSHRSNCAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107984936-B Reusable writing material and preparation method thereof 吉林大学 2022-05-06 CN disclosed
US-20100119561-A1 Compositions Having a Performance Indicator AMCOL INTERNATIONAL CORPORATION (US) 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119561-A1 Compositions Having a Performance Indicator STRA6, EXOSC5, CD63 CYP1A2 2197/4885HIF1A 3047/4885CYP2C9 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.