SCHEMBL3324095

SCHEMBL3324095

O=C(O)c1c(N=NNc2ccccc2)cccc1-c1cccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.39
TSHR P16473 1/20 0.39
CYP1B1 Q16678 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MEN1 O00255 8/20 0.39
KMT2A Q03164 8/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
GAA P10253 2/20 0.39
MAPT P10636 5/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 4/20 0.38
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520862 0.79 TDP1 (0.52) CYP1A1TSHRCYP1B1TDP1MEN1
SCHEMBL8520861 0.79 TDP1 (0.52) CYP1A1TSHRCYP1B1TDP1MEN1
SCHEMBL3324721 0.75 CYP1A2 (0.42) TSHRTDP1MEN1KMT2AGAA
SCHEMBL10783918 0.71 MEN1 (0.57) TDP1MEN1KMT2AKDM4EALDH1A1
Bicarbonate SCHEMBL11569280 0.70 NR4A1 (0.58) TDP1MEN1KMT2AKDM4EALDH1A1
SCHEMBL6555236 0.70 NR4A1 (0.66) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL28425561 0.70 CA12 (0.57) MEN1KMT2AGAAMAPTKDM4E
SCHEMBL29729196 0.68 ALDH1A1 (0.50) TSHRMEN1KMT2ANPC1RAB9A
Bicarbonate SCHEMBL27535643 0.68 NR4A1 (0.56) TDP1MEN1KMT2AKDM4EALDH1A1
SCHEMBL11426057 0.68 CYP3A4 (0.58) MEN1KMT2ANPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7588878-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-09-15 US claimed
US-7553603-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-06-30 US claimed
US-20080311518-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
US-20080311517-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
EP-2003503-A1 Inkless printing paper and method Xerox Corporation (US) 2008-12-17 EP claimed
US-20100119561-A1 Compositions Having a Performance Indicator AMCOL INTERNATIONAL CORPORATION (US) 2010-05-13 US disclosed
EP-2155156-A2 COMPOSITIONS HAVING A PERFORMANCE INDICATOR Amcol International Corporation (US) 2010-02-24 EP disclosed
US-7588878-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-09-15 US disclosed
US-7553603-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-06-30 US disclosed
US-20080311518-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311517-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US disclosed
EP-2003503-A1 Inkless printing paper and method Xerox Corporation (US) 2008-12-17 EP disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR CYP1A1 2466/4885TSHR 585/4885CYP1B1 1153/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT CYP1A1 1706/4885TSHR 4182/4885CYP1B1 2731/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 CYP1A1 2616/4885TSHR 4303/4885CYP1B1 2785/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH CYP1A1 3081/4885TSHR 4390/4885CYP1B1 1988/4885
US-20100119561-A1 Compositions Having a Performance Indicator STRA6, EXOSC5, CD63 CYP1A1 1992/4885TSHR 3470/4885CYP1B1 2670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.