SCHEMBL3326066

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3328133	0.83	HTR6 (0.46)	BRD4CYP3A4HTR6RORCKDM2B
	SCHEMBL3327805	0.83	CYP2C19 (0.52)	FGFR4CYP3A4HTR6CYP2C19
	SCHEMBL3328057	0.82	BRD4 (0.40)	BRD4FGFR4FGFR1FGFR2FGFR3
	Tert-Butyl Formate SCHEMBL27774752	0.76	HTR6 (0.42)	BRD4CYP3A4HTR6RORCKDM2B
	SCHEMBL3327909	0.76	RORC (0.49)	BRD4HTR6RORCKDM2BHDAC3
	Tert-Butyl Formate SCHEMBL27795729	0.76	CYP2C19 (0.42)	FGFR4CYP3A4HTR6HDAC3HDAC4
	SCHEMBL3323360	0.72	HTR6 (0.44)	CYP3A4HTR6HDAC3HDAC4HDAC1
	SCHEMBL3326162	0.72	HTR6 (0.46)	FGFR4CYP3A4HTR6
	SCHEMBL3327032	0.72	HTR6 (0.43)	BRD4CYP3A4HTR6RORCCHRNB2
	Tert-Butyl Formate SCHEMBL27774782	0.70	RORC (0.43)	BRD4HTR6RORCKDM2BHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.