Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324700 | 0.91 | BRD4 (0.42) | BRD4EPHX2NPSR1ALDH1A1KMT2A | |
| SCHEMBL10519951 | 0.87 | BRD4 (0.42) | BRD4EPHX2NPSR1ALDH1A1KDM4E | |
| SCHEMBL14599397 | 0.87 | BRD4 (0.44) | BRD4EPHX2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL27840927 | 0.84 | CYP3A4 (0.44) | BRD4CYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL9174869 | 0.83 | EPHX2 (0.43) | ALOX5EPHX2ALDH1A1KMT2ATSHR | |
| SCHEMBL10455924 | 0.83 | KMT2A (0.39) | ALOX5EPHX2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL9174861 | 0.83 | EPHX2 (0.43) | ALOX5EPHX2ALDH1A1KMT2ATSHR | |
| SCHEMBL10093470 | 0.79 | CHRNB2 (0.44) | BRD4EPHX2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14678837 | 0.79 | CHRNB2 (0.44) | BRD4EPHX2NPSR1ALDH1A1KMT2A | |
| SCHEMBL10093500 | 0.79 | CHRNB2 (0.44) | BRD4EPHX2NPSR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868964-B1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH & CIE (CH) | 2016-11-23 | — | — | EP | disclosed |
| EP-1868964-B1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH & CIE (CH) | 2016-11-23 | — | — | EP | disclosed |
| US-8692022-B2 | Hydrogenation of esters with Ru/bidentate ligands complexes | FIRMENICH SA (CH) | 2014-04-08 | — | — | US | disclosed |
| US-8692022-B2 | Hydrogenation of esters with Ru/bidentate ligands complexes | FIRMENICH SA (CH) | 2014-04-08 | — | — | US | disclosed |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2010-11-04 | — | — | US | disclosed |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2010-11-04 | — | — | US | disclosed |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2010-11-04 | — | — | US | disclosed |
| US-7763758-B2 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2010-07-27 | — | — | US | disclosed |
| US-7763758-B2 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2010-07-27 | — | — | US | disclosed |
| US-7763758-B2 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2010-07-27 | — | — | US | disclosed |
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA | 2010-05-27 | — | — | US | disclosed |
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA | 2010-05-27 | — | — | US | disclosed |
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA | 2010-05-27 | — | — | US | disclosed |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2008-03-20 | — | — | US | disclosed |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2008-03-20 | — | — | US | disclosed |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2008-03-20 | — | — | US | disclosed |
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | BRD4 104/4885ALOX5 1380/4885EPHX2 1313/4885 |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | ADH1C, ADH5, PHOSPHO1 | BRD4 276/4885ALOX5 1629/4885EPHX2 1539/4885 |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | BRD4 104/4885ALOX5 1380/4885EPHX2 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.