Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237972 | 0.84 | ENPP2 (0.63) | ENPP2MMP3TDP1KDM4EMEN1 | |
| Bromo Benzyl Cyanide SCHEMBL28326596 | 0.82 | TRPA1 (0.56) | ENPP2TAAR1MMP3IDO1AGXT | |
| Benzene SCHEMBL5438521 | 0.81 | ENPP2 (0.61) | ENPP2MMP3TDP1KDM4EMAOB | |
| SCHEMBL27802436 | 0.81 | PARP1 (0.40) | ENPP2TAAR1MMP3IDO1AGXT | |
| SCHEMBL521090 | 0.79 | MEN1 (0.73) | TAAR1IDO1AGXTTDP1MAOB | |
| SCHEMBL31135328 | 0.78 | PYCR1 (0.56) | TAAR1IDO1AGXTTDP1MAOB | |
| SCHEMBL2944694 | 0.78 | ENPP2 (0.53) | ENPP2MMP3TDP1KDM4EMEN1 | |
| SCHEMBL4769655 | 0.78 | PYCR1 (0.56) | TAAR1IDO1AGXTTDP1MAOB | |
| SCHEMBL4797497 | 0.78 | TAAR1 (0.55) | TAAR1IDO1AGXTTDP1MAOB | |
| SCHEMBL10821045 | 0.78 | TAAR1 (0.50) | TAAR1IDO1AGXTTDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 979 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894363-B | Synthesis process of 6-bromo-1, 2,3, 4-tetrahydroisoquinoline | 苏州艾缇克药物化学有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-116987027-B | Aggregation-induced emission photosensitizer and preparation method and application thereof | 深圳市儿童医院 | 2024-07-09 | — | — | CN | claimed |
| CN-116987027-A | Aggregation-induced emission photosensitizer and preparation method and application thereof | 深圳市儿童医院 | 2023-11-03 | — | — | CN | claimed |
| CN-115894363-A | Synthesis process of 6-bromo-1,2,3,4-tetrahydroisoquinoline | 苏州艾缇克药物化学有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-108002991-B | Visible light catalytic halogenated aromatic hydrocarbon dehalogenation method without photooxidation-reduction catalyst | 陕西师范大学 | 2021-01-05 | — | — | CN | claimed |
| CN-103880745-B | A kind of chemical synthesis process of the bromo- 1,2,3,4- tetrahydroisoquinoline -1- formic acid of 6- | 南通大学 | 2018-12-04 | — | — | CN | claimed |
| CN-108178743-A | A kind of Ai Le replaces the preparation method of Buddhist nun's key intermediate | 安庆奇创药业有限公司 | 2018-06-19 | — | — | CN | claimed |
| CN-103880745-A | Chemical synthesis method of 6-bromo-1,2,3,4-tetrahydroisoquinolyl-1-formic acid | UNIV NANTONG | 2014-06-25 | — | — | CN | claimed |
| CN-103396402-A | Substituted aminoindanes and analogs thereof and their pharmaceutical uses | SANOFI AVENTIS | 2013-11-20 | — | — | CN | claimed |
| CN-102203059-A | Substituted aminoindanes and analogs thereof and their pharmaceutical uses | SANOFI AVENTIS | 2011-09-28 | — | — | CN | claimed |
| CN-102190797-A | Quick synthesizing method of triazinyl covalent bond organic framework material with nano pores and application thereof | UNIV ANHUI | 2011-09-21 | — | — | CN | claimed |
| CN-102140074-A | Sulfonated aromatic dicarboxylic acid for synthesizing sulfonated polymer and preparation method of sulfonated aromatic carboxylic acid | UNIV SHANGHAI JIAOTONG | 2011-08-03 | — | — | CN | claimed |
| CN-101774871-A | Method for preparing biaryl compound in pure water solution | UNIV DALIAN TECH | 2010-07-14 | — | — | CN | claimed |
| CN-1639123-A | 4- (phenyl- (piperidin-4-yl) -amino) -benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | ASTRAZENECA AB (SE) | 2005-07-13 | — | — | CN | claimed |
| CN-1541203-A | 4- (phenyl- (piperidin-4 yl) -amino) -benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders | — | 2004-10-27 | — | — | CN | claimed |
| CN-122071475-A | Ternary condensed ring derivative and medical application thereof | 杭州百新生物医药科技有限公司 | 2026-05-22 | — | — | CN | disclosed |
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | SITRYX THERAPEUTICS LIMITED (GB) | 2026-05-05 | — | — | US | disclosed |
| EP-0302757-A2 | Anti-emetic serotonin depleting agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4369322-A | WITH CYANOGEN CHLORIDE | DEGUSSA AG (DE) | 1983-01-18 | — | — | US | disclosed |
| US-4252624-A | FREE RADICAL CATALYST, WATER | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ENPP2 1409/4885TAAR1 1278/4885MMP3 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.