Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31135328 | 1.00 | PYCR1 (0.56) | PYCR1TAAR1IDO1AGXTMAOB | |
| SCHEMBL9350384 | 0.84 | MEN1 (0.41) | PYCR1MAOBSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL5314627 | 0.79 | TAAR1 (0.57) | PYCR1TAAR1IDO1AGXTMAOB | |
| SCHEMBL26988528 | 0.79 | PYCR1 (0.41) | PYCR1TAAR1MAOBCYP1A2MAOA | |
| SCHEMBL26920214 | 0.78 | TSHR (0.42) | PYCR1MAOBSMN1; SMN2TDP1CYP1A2 | |
| SCHEMBL4797497 | 0.78 | TAAR1 (0.55) | PYCR1TAAR1IDO1AGXTMAOB | |
| SCHEMBL332680 | 0.78 | ENPP2 (0.53) | PYCR1TAAR1IDO1AGXTMAOB | |
| SCHEMBL10821045 | 0.78 | TAAR1 (0.50) | PYCR1TAAR1IDO1AGXTMAOB | |
| SCHEMBL9115020 | 0.75 | TAAR1 (0.47) | PYCR1TAAR1IDO1AGXTMAOB | |
| SCHEMBL10551659 | 0.75 | ALDH1A1 (0.39) | MAOBSMN1; SMN2TDP1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876507-B | Trisubstituted olefin tertiary phosphine compound and preparation method thereof | 湖北大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-112876507-A | Trisubstituted olefin tertiary phosphine compound and preparation method thereof | 湖北大学 | 2021-06-01 | — | — | CN | disclosed |
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |