SCHEMBL3328573

SCHEMBL3328573

C=C(CC(=O)CN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GABRR1 P24046 1/20 0.40
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39
GRM1 Q13255 1/20 0.39
GRM2 Q14416 1/20 0.39
GLRA1 P23415 1/20 0.38
SLC6A9 P48067 1/20 0.38
OR51E2 Q9H255 1/20 0.38
TET2 Q6N021 5/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5519615 0.78 ALOX15 (0.36) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL35851 0.77
SCHEMBL11304841 0.77 ALOX15 (0.43) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL3682486 0.77 KDM4E (0.46) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL1809603 0.76 ALOX15 (0.57) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL4579976 0.76 ALOX15 (0.58) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL10061456 0.76 ALOX15 (0.46) ALOX15HSD17B10GRIK1GRIK2GRM1
Hydrochloric Acid SCHEMBL734864 0.75
Itaconate SCHEMBL28033459 0.74 ALOX15 (0.62) ALOX15HSD17B10GABRR1GRIK1GRIK2
SCHEMBL8618420 0.74 TDP1 (0.45) ALOX15HSD17B10GRIK1GRIK2GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648811-B1 Thermoplastic resin compositions with high impact strength at low temperature CHEIL IND INC (KR) 1999-01-13 EP claimed
EP-0648811-A2 Thermoplastic resin compositions with high impact strength at low temperature CHEIL INDUSTRIES INC. (KR) 1995-04-19 EP claimed
JP-7288038-A None JP disclosed
JP-6223620-A None JP disclosed
JP-6163104-A None JP disclosed
US-20100132133-A1 KERATIN REACTING POLYMERIC STRUCTURES, THEIR SYNTHESIS AND USE EUDERMIC S.R.L. (IT) 2010-06-03 US disclosed
EP-2152229-A2 KERATIN REACTING POLYMERIC STRUCTURE, THEIR SYNTHESIS AND USE Eudermic S.r.l (IT) 2010-02-17 EP disclosed
WO-2008139312-A2 KERATIN REACTING POLYMERIC STRUCTURE, THEIR SYNTHESIS AND USE EUDERMIC S.R.L. (IT) 2008-11-20 WO disclosed
EP-0765912-B1 POLYESTER COMPOSITION AND FILMS PRODUCED THEREFROM TORAY INDUSTRIES (JP) 2008-11-05 EP disclosed
US-6559066-B2 Substrate for use in display element, method of manufacturing the same, and apparatus for manufacturing the same SHARP KABUSHIKI KAISHA (JP) 2003-05-06 US disclosed
US-20020018881-A1 Substrate for use in display element, method of manufacturing the same, and apparatus for manufacturing the same ALUSUISSE TECHNOLOGY AND MANAGEMENT LTD. ( A CORPORATION OF SWITZERLAND) (CH) 2002-02-14 US disclosed
US-6057038-A ORGANIC INSULATING FILM, AND EITHER AN INORGANIC INSULATING FILM OR TRANSPARENT CONDUCTIVE FILM; THE TWO FILMS ARE ADHERED WITH A SILANE COUPLING HAVING ALKOXY GROUP AND EITHER A POLYETHER, ALKYL, OR EPOXY GROUP; SILAZANE; OR CHLOROSILANE SHARP KABUSHIKI KAISHA (JP) 2000-05-02 US disclosed
EP-0648811-B1 Thermoplastic resin compositions with high impact strength at low temperature CHEIL IND INC (KR) 1999-01-13 EP disclosed
EP-0797778-A1 A METHOD FOR PREPARING NON-PROTEINACEOUS STRONGLY NEGATIVELY CHARGED MACROBIOMOLECULES, WHICH ARE LINKED TO PLASTIC KATHOLIEKE UNIVERSITEIT NIJMEGEN (NL) 1997-10-01 EP disclosed
EP-0765912-A1 POLYESTER COMPOSITION AND FILMS PRODUCED THEREFROM TORAY INDUSTRIES, INC. (JP) 1997-04-02 EP disclosed
WO-1996018905-A1 A METHOD FOR PREPARING NON-PROTEINACEOUS STRONGLY NEGATIVELY CHARGED MACROBIOMOLECULES, WHICH ARE LINKED TO PLASTIC KATHOLIEKE UNIVERSITEIT NIJMEGEN (NL) 1996-06-20 WO disclosed
JP-H07288038-A ELECTRICAL INSULATION RESIN COMPOSITION, WIRE, AND CABLE HITACHI CABLE LTD 1995-10-31 JP disclosed
EP-0648811-A2 Thermoplastic resin compositions with high impact strength at low temperature CHEIL INDUSTRIES INC. (KR) 1995-04-19 EP disclosed
JP-H06223620-A GOLD PASTE MATSUSHITA ELECTRIC IND CO LTD 1994-08-12 JP disclosed
JP-H06163104-A CONNECTOR YAZAKI CORP 1994-06-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100132133-A1 KERATIN REACTING POLYMERIC STRUCTURES, THEIR SYNTHESIS AND USE KRT18, F12, ILK ALOX15 1315/4885HSD17B10 4120/4885GABRR1 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.