SCHEMBL11304841

SCHEMBL11304841

C=C(CC(=O)CC(N)=O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
GRM1 Q13255 1/20 0.38
GRM2 Q14416 1/20 0.38
TET2 Q6N021 5/20 0.34
TET3 O43151 1/20 0.34
TET1 Q8NFU7 1/20 0.34
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514158 0.87
SCHEMBL4579976 0.79 ALOX15 (0.58) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL5481394 0.78 LMNA (0.44) ALOX15HSD17B10LDHALDHB
SCHEMBL3328573 0.77 ALOX15 (0.44) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL3682486 0.75 KDM4E (0.46) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL1809603 0.74 ALOX15 (0.57) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL4162002 0.74 ALOX15 (0.46) ALOX15HSD17B10GRIK1GRIK2GRM1
Itaconate SCHEMBL28196832 0.74 ALOX15 (0.65) ALOX15HSD17B10GRIK1GRIK2GRM1
SCHEMBL10061456 0.74 ALOX15 (0.46) ALOX15HSD17B10GRIK1GRIK2GRM1
Itaconate SCHEMBL28511688 0.74 ALOX15 (0.65) ALOX15HSD17B10GRIK1GRIK2GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4271237-A WEAR RESISTANT FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1981-06-02 US claimed
US-4217439-A CROSSLINKED DIACRYLATE-DIACETOACETAMIDE POLYMER ARMSTRONG CORK COMPANY (US) 1980-08-12 US claimed
US-4271237-A WEAR RESISTANT FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1981-06-02 US disclosed
US-4271237-A WEAR RESISTANT FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1981-06-02 US disclosed
US-4271237-A WEAR RESISTANT FLOOR COVERINGS ARMSTRONG CORK COMPANY (US) 1981-06-02 US disclosed
US-4217439-A CROSSLINKED DIACRYLATE-DIACETOACETAMIDE POLYMER ARMSTRONG CORK COMPANY (US) 1980-08-12 US disclosed
US-4217439-A CROSSLINKED DIACRYLATE-DIACETOACETAMIDE POLYMER ARMSTRONG CORK COMPANY (US) 1980-08-12 US disclosed
US-4217439-A CROSSLINKED DIACRYLATE-DIACETOACETAMIDE POLYMER ARMSTRONG CORK COMPANY (US) 1980-08-12 US disclosed