SCHEMBL3329259

SCHEMBL3329259

Brc1ccc2c(c1)c1cc(Br)ccc1n2-c1c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCLK1 O15075 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
CHEK2 O96017 1/20 0.42
CSF1R P07333 1/20 0.42
FER P16591 1/20 0.42
CDK2 P24941 1/20 0.42
MARK3 P27448 1/20 0.42
FLT4 P35916 1/20 0.42
FLT3 P36888 1/20 0.42
MAPK9 P45984 1/20 0.42
CSNK1D P48730 1/20 0.42
CLK2 P49760 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CSNK1G2 P78368 1/20 0.42
MAP4K2 Q12851 1/20 0.42
STK3 Q13188 1/20 0.42
CAMK2B Q13554 1/20 0.42
CAMK2G Q13555 1/20 0.42
DYRK1A Q13627 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299350 0.85 DCLK1 (0.41) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL20160994 0.83 ALDH1A1 (0.47) ALDH1A1MAPTKDM4EPTGS2ATM
SCHEMBL20161052 0.83 ALDH1A1 (0.47) ALDH1A1MAPTKDM4EPTGS2ATM
SCHEMBL22961327 0.79 ESR1 (0.40) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL31465156 0.78 MAPK14 (0.40) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL3326442 0.77 KDM4E (0.52) ALDH1A1MAPTKDM4EGAAATM
SCHEMBL560100 0.77 ALDH1A1 (0.48) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL30044892 0.77 ALDH1A1 (0.48) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL1832122 0.76 DNMT1 (0.38) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL1714949 0.76 L3MBTL1 (0.49) DCLK1PRKD3MAP4K4CHEK2CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461282-B2 (Pentaphenyl)phenyl group containing compound, polymeric derivative thereof and method for forming the same NATIONAL TAIWAN UNIVERSITY (TW) 2013-06-11 US disclosed
US-20100137461-A1 (Pentaphenyl)phenyl Group Containing Compound, Polymeric Derivative Thereof And Method For Forming The Same NATIONAL TAIWAN UNIVERSITY (TW) 2010-06-03 US disclosed
US-20080293945-A1 (Pentaphenyl)phenyl Group Containing Compound, Polymeric Derivative Thereof And Method For Forming The Same NATIONAL TAIWAN UNIVERSITY (TW) 2008-11-27 US disclosed