SCHEMBL20161052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20160994	1.00	ALDH1A1 (0.47)	ALDH1A1MAPK1KDM4EL3MBTL1ATM
	SCHEMBL20161053	0.89	ALDH1A1 (0.40)	ALDH1A1MAPK1KDM4EL3MBTL1ATM
	SCHEMBL20161111	0.89	ALDH1A1 (0.40)	ALDH1A1MAPK1KDM4EL3MBTL1ATM
	SCHEMBL3326442	0.89	KDM4E (0.52)	ALDH1A1KDM4EL3MBTL1ATMKMT2A
	SCHEMBL10029967	0.87	KDM4E (0.50)	ALDH1A1KDM4EL3MBTL1ATMKMT2A
	SCHEMBL14701623	0.84	L3MBTL1 (0.59)	ALDH1A1MAPK1KDM4EL3MBTL1ATM
	SCHEMBL3329259	0.83	DCLK1 (0.42)	ALDH1A1MAPK1KDM4EL3MBTL1ATM
	SCHEMBL20161195	0.81	L3MBTL1 (0.44)	ALDH1A1KDM4EL3MBTL1ATMKMT2A
	SCHEMBL12258328	0.77	KDM4E (0.52)	ALDH1A1KDM4EL3MBTL1ATMKMT2A
	SCHEMBL13777185	0.77	MAPK1 (0.64)	ALDH1A1MAPK1KDM4EL3MBTL1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.