SCHEMBL333024

SCHEMBL333024

c1ccc2c(CC3CO3)ccc(CC3CO3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 2/20 0.37
GLA P06280 1/20 0.37
CYP2D6 P10635 1/20 0.36
TSHR P16473 3/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
CHRM2 P08172 4/20 0.33
CHRM4 P08173 4/20 0.33
CHRM1 P11229 4/20 0.33
CHRM3 P20309 4/20 0.33
CHRM5 P08912 3/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC6A4 P31645 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6925336 0.98 DHFR (0.42) DHFRTDP1ALDH1A1GLACYP2D6
SCHEMBL1673416 0.91 CYP2D6 (0.40) DHFRTDP1ALDH1A1GLACYP2D6
Water SCHEMBL5597065 0.89 CYP2D6 (0.39) DHFRTDP1ALDH1A1GLACYP2D6
SCHEMBL845626 0.84 CYP2D6 (0.56) TDP1ALDH1A1CYP2D6KDM4EMEN1
SCHEMBL29826970 0.83 TDP1 (0.45) DHFRTDP1ALDH1A1GLATSHR
SCHEMBL6480647 0.83 TDP1 (0.45) DHFRTDP1ALDH1A1GLATSHR
SCHEMBL9250607 0.83 ALDH1A1 (0.53) DHFRTDP1ALDH1A1GLATSHR
Water SCHEMBL5605435 0.82 CYP2D6 (0.54) TDP1ALDH1A1CYP2D6KDM4EMEN1
SCHEMBL1673422 0.79 HSD17B10 (0.38) DHFRTDP1ALDH1A1CYP2D6TSHR
SCHEMBL3414921 0.79 DHFR (0.44) DHFRTDP1ALDH1A1GLATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851602-B2 Epoxide and fluorinated epoxide stabilizers for fluoroolefins THE CHEMOURS COMPANY FC, LLC (US) 2023-12-26 US claimed
US-20210380859-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS THE CHEMOURS COMPANY FC, LLC (US) 2021-12-09 US claimed
US-11130894-B2 Epoxide and fluorinated epoxide stabilizers for fluoroolefins THE CHEMOURS COMPANY FC, LLC (US) 2021-09-28 US claimed
US-20200115605-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS THE CHEMOURS COMPANY FC, LLC (US) 2020-04-16 US claimed
US-10550302-B2 Epoxide and fluorinated epoxide stabilizers for fluoroolefins THE CHEMOURS COMPANY FC, LLC (US) 2020-02-04 US claimed
EP-3470491-A1 PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS The Chemours Company FC, LLC (US) 2019-04-17 EP claimed
EP-2410032-B1 Phosphorus-containing stabilizers for fluoroolefins CHEMOURS CO FC LLC (US) 2018-11-14 EP claimed
US-20170362483-A1 EPOXIDE AND FLUORINATED EPOXIDE STABILIZERS FOR FLUOROOLEFINS THE CHEMOURS COMPANY FC, LLC 2017-12-21 US claimed
US-9777204-B2 Epoxide and fluorinated epoxide stabilizers for fluoroolefins THE CHEMOURS COMPANY FC, LLC (US) 2017-10-03 US claimed
EP-2420546-B1 Terephthalate stabilizers for fluoroolefins CHEMOURS CO FC LLC (US) 2017-04-26 EP claimed
CN-101522850-A Thiol and thioether stabilizers for fluoroolefins DU PONT (US) 2009-09-02 CN claimed
CN-101517032-A Ascorbic acid, terephthalate, or nitromethane stabilizers for fluoroolefins DU PONT (US) 2009-08-26 CN claimed
CN-101511967-A Phenol stabilizers for fluoroolefins DU PONT (US) 2009-08-19 CN claimed
EP-2069456-A1 AMINE STABILIZERS FOR FLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-17 EP claimed
US-20080157023-A1 Hydrofluoroalkene, an iodocarbon, a lubricant and a metal stabilizer; automotive air conditioning systems HONEYWELL INTERNATIONAL INC 2008-07-03 US claimed
WO-2008042066-A1 AMINE STABILIZERS FOR FLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-10 WO claimed
WO-2008027516-A1 LACTONES FOR FLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-06 WO claimed
WO-2007126760-A2 COMPOSITIONS COMPRISING IODOTRIFLUOROMETHANE AND STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-08 WO claimed
CN-1965049-A Stabilized trifluoroiodomethane compositions HONEYWELL INT INC (US) 2007-05-16 CN claimed
US-20060033072-A1 Stabilized trifluoroiodomethane compositions HONEYWELL INTERNATIONAL INC. (US) 2006-02-16 US claimed