Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417583 | 0.88 | ALDH1A1 (0.65) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL1715947 | 0.88 | ALDH1A1 (0.65) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL19859437 | 0.88 | ALDH1A1 (0.65) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL24452831 | 0.86 | ALDH1A1 (0.55) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL333024 | 0.83 | DHFR (0.43) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL729501 | 0.81 | ALDH1A1 (0.65) | ALDH1A1GLATDP1TP53TSHR | |
| Water SCHEMBL6925336 | 0.81 | DHFR (0.42) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL5517102 | 0.81 | ALDH1A1 (0.60) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL1129712 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL5511491 | 0.79 | ALDH1A1 (0.54) | ALDH1A1GLATDP1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380449-A | A phenol, an epoxide, mineral oil lubricant | ALLIEDSIGNAL INC. (US) | 1995-01-10 | — | — | US | claimed |
| WO-1992017560-A1 | STABILIZED CHLORINE-CONTAINING REFRIGERATION COMPOSITIONS | ALLIED-SIGNAL INC. (US) | 1992-10-15 | — | — | WO | claimed |
| WO-1992017559-A1 | STABILIZED DICHLOROTRIFLUOROETHANE REFRIGERATION COMPOSITIONS | ALLIED-SIGNAL INC. (US) | 1992-10-15 | — | — | WO | claimed |
| WO-1992017563-A1 | STABILIZED POLYOXYALKYLENE GLYCOLS | ALLIED-SIGNAL INC. (US) | 1992-10-15 | — | — | WO | claimed |
| US-5454966-A | Stabilizing composition of a phenol and fluorinated epoxide which reduces removal of chlorine or chlorine and fluorine from the chlorine-containing refrigerant; replacement of halogen with hydrogen; pollution control | ALLIEDSIGNAL INC. (US) | 1995-10-03 | — | — | US | disclosed |
| WO-1992018580-A1 | REFRIGERATION COMPOSITIONS OF HYDROFLUOROCARBON REFRIGERANT AND LUBRICANT | ALLIED-SIGNAL INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5156768-A | Prevents reaction of chlorine-containing refrigerant with hydrogen from lubricant | ALLIED-SIGNAL INC. (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1992017560-A1 | STABILIZED CHLORINE-CONTAINING REFRIGERATION COMPOSITIONS | ALLIED-SIGNAL INC. (US) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992017563-A1 | STABILIZED POLYOXYALKYLENE GLYCOLS | ALLIED-SIGNAL INC. (US) | 1992-10-15 | — | — | WO | disclosed |