Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59663 | 0.81 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL7478487 | 0.79 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL9619936 | 0.77 | — | — | |
| SCHEMBL3475820 | 0.77 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL10945743 | 0.77 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL6903428 | 0.74 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| Benzophenone SCHEMBL9310484 | 0.71 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 | |
| SCHEMBL6242759 | 0.69 | HDAC2 (0.31) | — | |
| SCHEMBL9848793 | 0.69 | CES2 (0.48) | ALDH1A1ATMMAPTRAB9ACES2 | |
| SCHEMBL19865171 | 0.68 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMTDP1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446698-B | Microbicidal quinoline (thio) carboxamide derivatives | 先正达参股股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20100144729-A1 | COUMARIN DERIVATIVES | NOVARTIS AG (CH) | 2010-06-10 | — | — | US | disclosed |
| EP-2109606-A1 | CHROMENE S1P1 RECEPTOR ANTAGONIST | Novartis Ag (CH) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008092930-A1 | CHROMENE S1P1 RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 2008-08-07 | — | — | WO | disclosed |
| EP-0234570-B1 | PHOTOPOLYMERIZABLE COMPOSITION, PHOTOSENSITIVE ELEMENT WITH THAT COMPOSITION, AND PROCESS FOR THE PRODUCTION OF A LITHOGRAPHIC PRINTING PLATE USING THIS ELEMENT | BASF Aktiengesellschaft (DE) | 1992-04-22 | — | — | EP | disclosed |
| US-4935330-A | Photopolymerizable mixture, photosensitive recording element containing this mixture, and the production of lithographic printing plate using this photosensitive recording element | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-19 | — | — | US | disclosed |
| EP-0234570-A2 | Photopolymerizable composition, photosensitive element with that composition, and process for the production of a lithographic printing plate using this element | BASF Aktiengesellschaft (DE) | 1987-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144729-A1 | COUMARIN DERIVATIVES | F3, CYP3A7, CYP3A4 | ALDH1A1 60/4885L3MBTL1 1716/4885ATM 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.