SCHEMBL59663

SCHEMBL59663

O=C1CC=CC=C1C(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
HPGD P15428 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
BLM P54132 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SRD5A2 P31213 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL2938803 0.85 NOS3 (0.36) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL9848793 0.84 CES2 (0.48) ALDH1A1MAPTATMRAB9ALMNA
SCHEMBL5327293 0.83 ALDH1A1 (0.47) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL9459241 0.82
SCHEMBL19718080 0.81 AKR1C3 (0.46) ALDH1A1KMT2AHSD17B10CYP3A4ALOX15
SCHEMBL7478487 0.81 ALDH1A1 (0.43) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL3330849 0.81 ALDH1A1 (0.43) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL10945743 0.78 ALDH1A1 (0.41) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL3475820 0.78 ALDH1A1 (0.41) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL11408663 0.78 HPGD (0.40) ALDH1A1HPGDMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023227472-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2023-11-30 WO claimed
CN-115160653-A Quarter wave plate and preparation method and application thereof 中国科学技术大学 2022-10-11 CN claimed
CN-110613630-B Sunscreen cream containing benzophenone derivative nanocrystals and preparation method thereof 汕头大学 2022-08-30 CN claimed
CN-114574081-A Preparation method of heavy-duty anticorrosive protective coating for metal surface 中国石油化工股份有限公司 2022-06-03 CN claimed
CN-113698832-A Self-cleaning outdoor water-based nano tin antimony oxide-silicon dioxide/silicon acrylic composite transparent heat-insulating coating and preparation method thereof 嘉宝莉化工集团股份有限公司 2021-11-26 CN claimed
CN-113573688-A Effective sunscreen compositions with diethylamino hydroxybenzoyl hexyl benzoate, butyl methoxydibenzoyl methane and organic particulate UV filters 巴斯夫欧洲公司 2021-10-29 CN claimed
CN-113573693-A Effective sunscreen compositions with diethylamino hydroxybenzoyl hexyl benzoate and water soluble UVA filters 巴斯夫欧洲公司 2021-10-29 CN claimed
CN-109065239-B B1-grade high-flame-retardant green environment-friendly low-voltage alternating-current cable for smart power grid and manufacturing process 江苏亨通电力电缆有限公司 2020-04-10 CN claimed
CN-110613630-A Sunscreen cream containing benzophenone derivative nanocrystals and preparation method thereof 汕头大学 2019-12-27 CN claimed
CN-108368462-A Include the cleaning sheet of functional particles 株式会社LG生活健康 2018-08-03 CN claimed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO claimed
EP-0294073-B1 PREPARATION OF ESTERS Interox Chemicals Limited (GB) 1991-12-11 EP claimed
US-4908474-A Treating alkali metal phenol sulfonate with equimolar amount of benzoyl chloride and restricted amount of water and base INTEROX CHEMICALS LIMITED (GB) 1990-03-13 US claimed
EP-0294073-A1 Preparation of esters Interox Chemicals Limited (GB) 1988-12-07 EP claimed
US-4413075-A POLYMERIZATION FROM PIPERIDINE-4-SPIRO-OXIRANES MONTEDISON S.P.A. (IT) 1983-11-01 US claimed
US-4373042-A OXIDATION, HEAT, AND SUNLIGHT RESISTANCE MONTEDISON S.P.A. (IT) 1983-02-08 US claimed
EP-0050410-A1 Method of enhancing flammability resistance of polyparabanic acid films by the addition of copper chelates and films thus formed EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-04-28 EP claimed
US-4317767-A N-ALKYL-PIPERIDINE DERIVATIVES OF HYDROXY-BENZYL-MALONIC ACID MONTEDISON S.P.A. (IT) 1982-03-02 US claimed
US-4293466-A Piperidine phosphite stabilizers for polymers and polymers stabilized thereby MONTEDISON S.P.A. (IT) 1981-10-06 US claimed
US-4104248-A Polyolefine-based polymeric compositions stabilized by organic polyamines, textile fibers obtained therefrom, and novel organic polyamines MONTEFIBRE S.P.A. (IT) 1978-08-01 US claimed