SCHEMBL333372

SCHEMBL333372

C=CCc1cc(Br)cc(C)c1O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
GAA P10253 3/20 0.40
GABRA1 P14867 3/20 0.39
GABRB2 P47870 3/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 1/20 0.39
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
GLA P06280 1/20 0.35
SHBG P04278 1/20 0.35
POLB P06746 1/20 0.34
AKR1B1 P15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331989 0.81 GAA (0.53) ALOX5PTGS1PTGS2GAAGABRA1
SCHEMBL14283804 0.81 ALOX5 (0.49) ALOX5PTGS1PTGS2GAAGABRA1
SCHEMBL7582780 0.81 CYP3A4 (0.50) GAAGABRA1GABRB2KMT2AMEN1
SCHEMBL9115480 0.79 ALOX5 (0.48) ALOX5PTGS1PTGS2GAAGABRA1
SCHEMBL27771899 0.79 SHBG (0.48) ALOX5PTGS1PTGS2GAAGABRA1
SCHEMBL9908791 0.79 PTGS1 (0.45) ALOX5PTGS1PTGS2GAAGABRA1
SCHEMBL14742304 0.78 GABRA1 (0.39) ALOX5GAAGABRA1GABRB2KMT2A
SCHEMBL6946900 0.78 SHBG (0.61) ALOX5PTGS1PTGS2GAAGABRA1
SCHEMBL4230006 0.78 GABRA1 (0.39) GAAGABRA1GABRB2KMT2AMEN1
SCHEMBL1620174 0.77 GAA (0.51) ALOX5PTGS1GAAGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720194-A1 POLYCARBONATE COPOLYMER COMPOSITIONS SHPP Global Technologies B.V. (NL) 2026-04-08 EP disclosed
US-12577391-B2 Chemically-resistant flame retardant compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-17 US disclosed
EP-4305105-B1 THERMOPLASTIC COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2026-02-18 EP disclosed
US-20260001986-A1 THERMOPLASTIC COMPOSITION FOR LASER DIRECT STRUCTURING MCE TECHNICAL CENTER B V (NL) 2026-01-01 US disclosed
EP-4056603-B1 COMPOSITION OF METHACRYLATE (CO)POLYMER AND POLY(CARBONATE-SILOXANE) BLOCKCOPOLYMER AND ITS USE IN SCRATCH AND IMPACT RESITANT ARTICLES SHPP GLOBAL TECH BV (NL) 2025-12-03 EP disclosed
US-20250320358-A1 ANTI-DRIP POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECH BV (NL) 2025-10-16 US disclosed
EP-4619474-A1 CHEMICALLY RESISTANT POLYCARBONATE COMPOSITIONS AND ARTICLES MADE THEREFROM SHPP Global Technologies B.V. (NL) 2025-09-24 EP disclosed
US-20250289953-A1 ANTI-DRIP POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-09-18 US disclosed
EP-4101894-B1 THERMOPLASTIC COMPOSITIONS AND SHAPED ARTICLES THEREOF SHPP GLOBAL TECH BV (NL) 2025-07-23 EP disclosed
EP-4585645-A1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS SHPP Global Technologies B.V. (NL) 2025-07-16 EP disclosed
US-20050095433-A1 Multilayered articles and method of manufacture thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2005-05-05 US disclosed
US-20040220330-A1 Transparent and high-heat polycarbonate-polysiloxane copolymers and transparent blends with polycarbonate and a process for preparing same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-11-04 US disclosed
WO-2004076512-A2 TRANSPARENT AND HIGH-HEAT POLYCARBONATE-POLYSILOXANE COPOLYMERS AND TRANSPARENT BLENDS WITH POLYCARBONATE AND A PROCESS FOR PREPARING SAME GENERAL ELECTRIC COMPANY (US) 2004-09-10 WO disclosed
WO-2004076541-A2 TRANSLUCENT THERMOPLASTIC COMPOSITION, METHOD FOR MAKING THE COMPOSITION AND ARTICLES MOLDED THERE FROM. GENERAL ELECTRIC COMPANY (US) 2004-09-10 WO disclosed
EP-1272543-A1 METHOD FOR MAKING SILOXANE COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-01-08 EP disclosed
WO-2001053380-A1 METHOD FOR MAKING SILOXANE COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2001-07-26 WO disclosed
US-6252013-B1 MELT PROCESSABILITY GENERAL ELECTRIC COMPANY 2001-06-26 US disclosed
US-5530083-A ADDIN PHOSGENE TO BISPHENOL IN THE PRESENCE OF PHASE TRANSFER CATALYST, ADDING EXCESS PHOSGENE TO GENERATE CHLOROFORMATE END GROUPS, ADDING POLYSILOXANE GENERAL ELECTRIC COMPANY (US) 1996-06-25 US disclosed
US-5357022-A Flame retarders; oxidative coupling a diorganophenol with a silicone GENERAL ELECTRIC COMPANY (US) 1994-10-18 US disclosed
EP-0540273-A1 Thermoplastic silicone-polyphenylene ether block copolymers GENERAL ELECTRIC COMPANY (US) 1993-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001986-A1 THERMOPLASTIC COMPOSITION FOR LASER DIRECT STRUCTURING DYNLL2, PUM2, DYNLL1 ALOX5 1597/4885PTGS1 4054/4885PTGS2 3000/4885
US-12577391-B2 Chemically-resistant flame retardant compositions RPL3, RPL4, UFM1 ALOX5 2118/4885PTGS1 4436/4885PTGS2 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.