Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.31 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363792 | 0.85 | TSHR (0.40) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL29017306 | 0.82 | PLOD2 (0.32) | GAAPLOD2PLOD3PLOD1 | |
| SCHEMBL9286605 | 0.81 | MAPT (0.36) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL57069 | 0.80 | TSHR (0.52) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL11559276 | 0.80 | TSHR (0.46) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| Lithium SCHEMBL31366079 | 0.78 | TSHR (0.50) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL8865453 | 0.78 | TSHR (0.50) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL16691063 | 0.77 | ALDH1A1 (0.41) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL6032404 | 0.77 | TSHR (0.40) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL4767550 | 0.76 | TSHR (0.48) | TDP1TSHRMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022259210-A1 | NOVEL PROCESS FOR PREPARATION OF 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-OL | INCOR RENOVIS PHARMA PRIVATE LIMITED (IN) | 2022-12-15 | — | — | WO | claimed |
| EP-3486241-B1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2022-05-04 | — | — | EP | claimed |
| US-20210323943-A1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-10-21 | — | — | US | claimed |
| US-10752608-B2 | Method for producing crystal of uracil compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-08-25 | — | — | US | claimed |
| WO-2020148780-A1 | PROCESS FOR PREPARATION OF 4,4,4- TRIFLUOROBUT-2-EN-1-OL AND INTERMEDIATE THEREOF | SRF LIMITED (IN) | 2020-07-23 | — | — | WO | claimed |
| US-10717723-B2 | — | — | 2020-07-21 | — | — | US | claimed |
| US-20190263780-A1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-08-29 | — | — | US | claimed |
| EP-3486241-A1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | Sumitomo Chemical Company Limited (JP) | 2019-05-22 | — | — | EP | claimed |
| EP-0599036-B1 | Method for the preparation of 2-aryl-5-trifluoromethyl pyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0599036-A1 | Method for the preparation of 2-aryl-5-trifluoromethyl pyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| US-5256796-A | Method for the preparation of 2-aryl-5-trifluoromethylpyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-10-26 | — | — | US | claimed |
| EP-0270724-B1 | PREPARATION OF ALKYL TRIFLUOROACETOACETATE | Monsanto Company (US) | 1990-11-28 | — | — | EP | claimed |
| EP-0270724-A1 | Preparation of alkyl trifluoroacetoacetate | Monsanto Company (US) | 1988-06-15 | — | — | EP | claimed |
| US-4647689-A | Preparation of alkyl trifluoroacetoacetate | MONSANTO COMPANY (US) | 1987-03-03 | — | — | US | claimed |
| WO-2022259210-A1 | NOVEL PROCESS FOR PREPARATION OF 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-OL | INCOR RENOVIS PHARMA PRIVATE LIMITED (IN) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022259210-A1 | NOVEL PROCESS FOR PREPARATION OF 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-OL | INCOR RENOVIS PHARMA PRIVATE LIMITED (IN) | 2022-12-15 | — | — | WO | disclosed |
| EP-3486241-B1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-4647689-A | Preparation of alkyl trifluoroacetoacetate | MONSANTO COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| US-4647689-A | Preparation of alkyl trifluoroacetoacetate | MONSANTO COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| US-4647689-A | Preparation of alkyl trifluoroacetoacetate | MONSANTO COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717723-B2 | — | C5, UMPS, C9 | TDP1 289/4885TSHR 4108/4885MAPT 1164/4885 |
| US-20210323943-A1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | UMPS, UGP2, UNG | TDP1 303/4885TSHR 3906/4885MAPT 1106/4885 |
| US-20190263780-A1 | METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND | UMPS, UGP2, UNG | TDP1 310/4885TSHR 3900/4885MAPT 1086/4885 |
| US-10752608-B2 | Method for producing crystal of uracil compound | UMPS, UGP2, UNG | TDP1 310/4885TSHR 3900/4885MAPT 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.