Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3333968 | 0.81 | TDP1 (0.42) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL9251998 | 0.75 | MAPT (0.39) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL8988263 | 0.71 | FAAH (0.37) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL1082749 | 0.71 | CYP3A4 (0.41) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL4864146 | 0.71 | CYP3A4 (0.32) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL11668025 | 0.70 | MAPT (0.36) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL28761387 | 0.70 | CYP3A4 (0.39) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL28427366 | 0.70 | CYP3A4 (0.39) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL11444238 | 0.70 | CYP3A4 (0.39) | MAPTCACNA1BAPBA1CYP3A4TDP1 | |
| SCHEMBL29506833 | 0.70 | CYP3A4 (0.39) | MAPTCACNA1BAPBA1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496720-B1 | Process for producing hemiketals and hemithioketals | ROHM & HAAS (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0496720-A1 | Process for producing hemiketals and hemithioketals | ROHM AND HAAS COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |
| US-5113008-A | Process for producing hemiketals and hemithioketals | MONSANTO COMPANY (US) | 1992-05-12 | — | — | US | disclosed |