SCHEMBL3334217

SCHEMBL3334217

CCN(CC)C(=O)[C@@H]1[C@@H](CC(=N)NC(=N)N)C(=O)N1C(=O)N[C@H](C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.37
F11 P03951 10/20 0.37
CCR5 P51681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3335635 0.88 TPSAB1 (0.41) CMA1F11
SCHEMBL3338358 0.86 CMA1 (0.40) CMA1
SCHEMBL3338244 0.80 CMA1 (0.39) CMA1F11
SCHEMBL3330783 0.79 TPSAB1 (0.39) CMA1F11
SCHEMBL3334212 0.78 CMA1 (0.38) CMA1F11CCR5
SCHEMBL3330810 0.78 ATM (0.41) CMA1
Trifluoroacetic Acid SCHEMBL3339731 0.71 F11 (0.59) F11
SCHEMBL3336687 0.71 TPSAB1 (0.48) CMA1
SCHEMBL3333854 0.71 TPSAB1 (0.48) CMA1
SCHEMBL3339780 0.71 TPSAB1 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100144698-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2010-06-10 US disclosed
US-20090143351-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2009-06-04 US disclosed
US-7501404-B2 Substituted azetidinones DAIMED (US) 2009-03-10 US disclosed
US-20070105832-A1 Substituted azetidinones Cadrenal Therapeutics, Inc. 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105832-A1 Substituted azetidinones F2R, CPA3, CFD CMA1 12/4885F11 17/4885CCR5 1128/4885
US-20100144698-A1 SUBSTITUTED AZETIDINONES F2R, CPA3, CFD CMA1 12/4885F11 17/4885CCR5 1128/4885
US-20090143351-A1 SUBSTITUTED AZETIDINONES F2R, CPA3, CFD CMA1 12/4885F11 17/4885CCR5 1128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.