Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680869 | 0.89 | L3MBTL1 (0.41) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL21268272 | 0.88 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL21268391 | 0.88 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL21268355 | 0.86 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL21268350 | 0.83 | CYP1A2 (0.37) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL677792 | 0.83 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19L3MBTL1LTA4H | |
| SCHEMBL11125422 | 0.81 | CYP2C9 (0.43) | CYP1A2CYP2C9CYP2C19MAPTLTA4H | |
| SCHEMBL27677203 | 0.80 | MAPT (0.40) | CYP1A2CYP2C9CYP2C19MAPTHPGD | |
| SCHEMBL21268352 | 0.80 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL21268377 | 0.80 | MAPT (0.41) | MAPTL3MBTL1HPGDATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | CYP1A2 146/4885CYP2C9 480/4885CYP2C19 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.