SCHEMBL3336026

SCHEMBL3336026

CCCCCCCCCCCCCCCCC(C(N)=O)(C(C)O)C(O)CCCCCCCCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.41
GPR84 Q9NQS5 7/20 0.41
FFAR1 O14842 2/20 0.41
SPHK1 Q9NYA1 1/20 0.41
FFAR4 Q5NUL3 1/20 0.38
CA1 P00915 1/20 0.37
EPHX1 P07099 1/20 0.37
SCN5A Q14524 3/20 0.36
SCN9A Q15858 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10698693 0.88 EPHX1 (0.42) ACE2GPR84EPHX1SCN5ASCN9A
SCHEMBL2800331 0.81 FAAH (0.54)
SCHEMBL5313151 0.81 FAAH (0.54)
SCHEMBL11398423 0.79 EPHX1 (0.43) ACE2EPHX1SCN5ASCN9A
SCHEMBL28064279 0.78 ACE2 (0.44) ACE2GPR84FFAR1SPHK1CA1
SCHEMBL29010539 0.77 GPR84 (0.43) ACE2GPR84FFAR1SPHK1FFAR4
SCHEMBL28984579 0.75 GPR84 (0.40) ACE2GPR84FFAR1SPHK1FFAR4
SCHEMBL29118740 0.74 GPR84 (0.38) ACE2GPR84FFAR1FFAR4
SCHEMBL5465134 0.73 ACE2 (0.55) ACE2GPR84FFAR1SPHK1CA1
SCHEMBL28648915 0.72 CYP1A2 (0.38) ACE2GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080031908-A1 OILY COSMETIC COMPOSITION IN AEROSOL FORM L'OREAL (FR) 2008-02-07 US claimed
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS CIBA CORPORATION (US) 2010-06-10 US disclosed
EP-2120846-A2 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS BASF SE (DE) 2009-11-25 EP disclosed
WO-2008107347-A2 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS BASF SE (CH) 2008-09-12 WO disclosed
EP-1891925-A1 Oily cosmetic composition in aerosol form L'Oréal (FR) 2008-02-27 EP disclosed
US-20080031908-A1 OILY COSMETIC COMPOSITION IN AEROSOL FORM L'OREAL (FR) 2008-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS MAOA, MAOB, ACMSD ACE2 3061/4885GPR84 3594/4885FFAR1 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.