SCHEMBL3338156

SCHEMBL3338156

CCCCCCCCCCCCCCCC(=O)c1c(CCN)c2ccccc2n1OC

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OXER1 Q8TDS5 1/20 0.42
▸ PLA2G2A P14555 4/20 0.41
▸ TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27673202 0.75 MCL1 (0.48) —
SCHEMBL286699 0.73 OXER1 (0.53) OXER1TSHR
SCHEMBL287042 0.71 OXER1 (0.68) OXER1TSHR
SCHEMBL28665614 0.69 MEN1 (0.44) —
SCHEMBL1066222 0.68 OXER1 (0.72) OXER1
SCHEMBL1063485 0.68 OXER1 (0.72) OXER1
SCHEMBL22411434 0.68 OXER1 (0.72) OXER1
SCHEMBL28846994 0.67 HTR7 (0.48) —
SCHEMBL25292726 0.66 IL1R1 (0.42) —
SCHEMBL9263671 0.66 MCL1 (0.61) OXER1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040022822-A1 Cosmetic compositions containing keratinization modulators and methods for improving keratinous surfaces REVLON CONSUMER PRODUCTS CORPORATION (US) 2004-02-05 — — US claimed
US-20020034524-A1 Cosmetic compositions containing keratinization modulators and methods for improving keratinous surfaces REVLON CONSUMER PRODUCTS CORPORATION 2002-03-21 — — US claimed
WO-2002000176-A1 COSMETIC COMPOSITIONS CONTAINING KERATINIZATION MODULATORS AND METHODS FOR IMPROVING KERATINOUS SURFACES REVLON CONSUMER PRODUCTS CORPORATION (US) 2002-01-03 — — WO claimed
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS CIBA CORPORATION (US) 2010-06-10 — — US disclosed
EP-1408912-B1 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS DOW CORNING (US) 2007-03-07 — — EP disclosed
EP-1408912-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS Dow Corning Corporation (US) 2004-04-21 — — EP disclosed
US-20040022822-A1 Cosmetic compositions containing keratinization modulators and methods for improving keratinous surfaces REVLON CONSUMER PRODUCTS CORPORATION (US) 2004-02-05 — — US disclosed
WO-2003009819-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS DOW CORNING CORPORATION (US) 2003-02-06 — — WO disclosed
US-6498197-B1 Temperature insensitive one-phase microemulsions DOW CORNING CORPORATION 2002-12-24 — — US disclosed
US-6455058-B1 ANTIDANDRUFF AGENT SUCH AS SALICYLIC ACID, (2) A POLYETHYLENIMINE, AND (3) AN AMPHOTERIC SURFACTANT. THE COMPOSITION PROVIDES SUPERIOR EFFECTS FOR REPAIRING DAMAGED HAIR, PROTECTING HAIR AGAINST CHEMICAL AND MECHANICAL DAMAGE AMITEE COSMETICS, INC. 2002-09-24 — — US disclosed
US-20020034524-A1 Cosmetic compositions containing keratinization modulators and methods for improving keratinous surfaces REVLON CONSUMER PRODUCTS CORPORATION 2002-03-21 — — US disclosed
WO-2002000176-A1 COSMETIC COMPOSITIONS CONTAINING KERATINIZATION MODULATORS AND METHODS FOR IMPROVING KERATINOUS SURFACES REVLON CONSUMER PRODUCTS CORPORATION (US) 2002-01-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS MAOA, MAOB, ACMSD OXER1 167/4885PLA2G2A 4469/4885TSHR 2456/4885
US-20020034524-A1 Cosmetic compositions containing keratinization modulators and methods for improving keratinous surfaces KRT18, MC1R, HTR6 OXER1 1404/4885PLA2G2A 346/4885TSHR 575/4885
US-20040022822-A1 Cosmetic compositions containing keratinization modulators and methods for improving keratinous surfaces KRT18, MC1R, HTR6 OXER1 1404/4885PLA2G2A 346/4885TSHR 575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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