Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 2/20 | 0.51 |
| ▸ | SKP1 | P63208 | 2/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30548164 | 0.95 | GPR119 (0.50) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL24266531 | 0.95 | GPR119 (0.50) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL3111974 | 0.83 | CKS1B (0.54) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL4531400 | 0.83 | HRH3 (0.56) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL29574249 | 0.83 | GPR119 (0.56) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL24265269 | 0.83 | GPR119 (0.56) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL461584 | 0.82 | CKS1B (0.62) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL23839560 | 0.82 | MAP4K4 (0.55) | GPR119MAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL5352757 | 0.81 | ALOX5AP (0.52) | GPR119 | |
| SCHEMBL3103887 | 0.81 | GPR119 (0.51) | GPR119MAP4K4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CYP51A1, ERG28, CYP3A7 | GPR119 1356/4885MAP4K4 2647/4885CKS1B 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.