Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17293168 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTMALT1COMTS1PR1 | |
| SCHEMBL17293158 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTMALT1COMTS1PR1 | |
| SCHEMBL21030730 | 0.79 | MALT1 (0.46) | ALDH1A1MAPTMALT1COMTSMN1; SMN2 | |
| SCHEMBL21030631 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTMALT1COMTS1PR1 | |
| SCHEMBL23495764 | 0.77 | CYP1A2 (0.37) | COMTGABRG2GABRB3GABRA5SMN1; SMN2 | |
| SCHEMBL17293038 | 0.77 | MALT1 (0.42) | ALDH1A1MAPTMALT1COMTSMN1; SMN2 | |
| SCHEMBL18820154 | 0.76 | MALT1 (0.42) | ALDH1A1MAPTMALT1COMTS1PR1 | |
| SCHEMBL332643 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTCOMTGABRG2GABRB3 | |
| SCHEMBL333926 | 0.73 | KMT2A (0.41) | ALDH1A1MAPTSMN1; SMN2S1PR1PLAU | |
| SCHEMBL21858874 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTMALT1COMTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387964-A1 | HETEROARYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-16 | — | — | US | disclosed |
| WO-2020079167-A1 | HETEROARYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
| US-8097733-B2 | Pyrazole derivatives as 5-LO-inhibitors | PFIZER INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090227634-A1 | Pyrazole Derivatives as 5-LO-Inhibitors | PFIZER INC. | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227634-A1 | Pyrazole Derivatives as 5-LO-Inhibitors | ALOX5, ALOX15, CYP3A5 | ALDH1A1 224/4885MAPT 4364/4885MALT1 2368/4885 |
| US-20210387964-A1 | HETEROARYLAMINOQUINOLINES AND ANALOGUES | PIK3C3, ERG28, CBR3 | ALDH1A1 2522/4885MAPT 3418/4885MALT1 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.