Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | TP53 | P04637 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CASP1 | P29466 | 4/20 | 0.52 |
| ▸ | CASP7 | P55210 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036073 | 0.92 | MAPT (0.57) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL3343972 | 0.91 | PPARG (0.55) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL4038498 | 0.88 | PPARG (0.54) | ABCB1MAPTCYP3A4KDM4EMEN1 | |
| SCHEMBL4035471 | 0.85 | MAPT (0.65) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL13648830 | 0.85 | PPARG (0.53) | MAPTCYP3A4KDM4EMEN1KMT2A | |
| SCHEMBL30667382 | 0.85 | ABCG2 (0.58) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL13654306 | 0.84 | ABCG2 (0.53) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL4035682 | 0.82 | MAPT (0.49) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL6897378 | 0.80 | ABCB1 (0.72) | ABCB1MAPTCYP3A4KDM4ETP53 | |
| SCHEMBL25022832 | 0.79 | ABCG2 (0.73) | ABCB1MAPTCYP3A4KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100151508-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| EP-2087350-A1 | COMPOUNDS | The Robert Gordon University (GB) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008062184-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY (GB) | 2008-05-29 | — | — | WO | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| US-20060137207-A1 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |
| EP-1534698-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | The Rowett Research Institute (GB) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004007475-A1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RESEARCH INSTITUTE (GB) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151508-A1 | COMPOUNDS | NFE2L2, RBBP4, GPX4 | ABCB1 736/4885MAPT 3919/4885CYP3A4 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.