Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038498 | 0.97 | PPARG (0.54) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL13648830 | 0.94 | PPARG (0.53) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL3339178 | 0.91 | ABCB1 (0.53) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL12685815 | 0.83 | ABCG2 (0.49) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL4036073 | 0.83 | MAPT (0.57) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4039498 | 0.82 | PPARG (0.50) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL3340894 | 0.82 | PPARG (0.50) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4035989 | 0.82 | PPARG (0.50) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL15307575 | 0.82 | PPARG (0.52) | PPARGABCG2KDM4EALDH1A1HPGD | |
| SCHEMBL4042000 | 0.81 | PPARG (0.51) | PPARGABCG2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359323-B2 | Compound | MCPHAIL DONALD BARTON (GB) | 2016-06-07 | — | — | US | disclosed |
| US-9359323-B2 | Compound | MCPHAIL DONALD BARTON (GB) | 2016-06-07 | — | — | US | disclosed |
| US-20130267586-A1 | Compound | ANTOXIS LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| US-20130267586-A1 | Compound | ANTOXIS LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |
| EP-2627646-A1 | COMPOUND | Antoxis Limited (GB) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012049460-A1 | COMPOUND | ANTOXIS LIMITED (GB) | 2012-04-19 | — | — | WO | disclosed |
| US-20100151508-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-20100151508-A1 | COMPOUNDS | THE ROBERT GORDON UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| US-7601754-B2 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2009-10-13 | — | — | US | disclosed |
| EP-1534698-B1 | FLAVONOID COMPOUNDS AS THERAPEUTIC ANTIOXIDANTS | ROWETT RES INST (GB) | 2007-09-19 | — | — | EP | disclosed |
| US-20060137207-A1 | Flavonoid compounds as therapeutic antioxidants | ANTOXIS LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151508-A1 | COMPOUNDS | NFE2L2, RBBP4, GPX4 | PPARG 2562/4885ABCG2 266/4885KDM4E 1425/4885 |
| US-20130267586-A1 | Compound | TYR, NQO1, GLA | PPARG 1450/4885ABCG2 3994/4885KDM4E 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.