SCHEMBL333922

SCHEMBL333922

c1cc2c3c4c(ccc3c1)CCCC4CC2

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
MTNR1A P48039 2/20 0.37
MTNR1B P49286 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232003 1.00 CYP3A4 (0.38) CYP3A4TSHRADRA2AADRA2BADRA2C
SCHEMBL28989799 0.97 ADRA2A (0.36) CYP3A4TSHRADRA2AADRA2BADRA2C
SCHEMBL27291641 0.94 ADRA2A (0.40) ADRA2AADRA2BADRA2CMTNR1AMTNR1B
SCHEMBL718791 0.82 TSHR (0.40) TSHR
SCHEMBL30739530 0.82 TSHR (0.40) TSHR
SCHEMBL829452 0.78 TSHR (0.43) TSHRADRA2AADRA2C
SCHEMBL28646514 0.74 KDM4E (0.41) CYP3A4TSHRADRA2AADRA2BADRA2C
SCHEMBL25381760 0.73 PDPK1 (0.40)
SCHEMBL334090 0.73 MTNR1B (0.35) CYP3A4TSHRADRA2AADRA2BADRA2C
SCHEMBL5013339 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673257-A1 PROCESS FOR PRODUCING GUERBET ALCOHOLS FROM FUSEL ALCOHOLS Terra Mater BV (BE) 2026-01-07 EP claimed
WO-2024180214-A1 PROCESS FOR PRODUCING GUERBET ALCOHOLS FROM FUSEL ALCOHOLS Terra Mater BV (BE) 2024-09-06 WO claimed
CN-118561233-A Liquid hydrogen storage composition and preparation method thereof 武汉氢阳能源有限公司 2024-08-30 CN claimed
CN-109851462-B Production method of medical intermediate hexadecahydropyrene 中国石油化工股份有限公司 2022-03-08 CN claimed
CN-109852420-B Preparation and purification process of hexadecahydropyrene 中国石油化工股份有限公司 2021-04-06 CN claimed
CN-110257101-B Device and method for preparing chemicals through reaction-separation-reaction of coal tar distillate 西北大学 2021-03-30 CN claimed
CN-111471233-A Polyvinyl degradable plastic and preparation method thereof 浙江钦堂钙业股份有限公司 2020-07-31 CN claimed
CN-110257101-A A kind of coal tar fraction reaction-separation-reaction prepares the device and method of chemicals 西北大学 2019-09-20 CN claimed
CN-107653002-B A method of condensed-nuclei aromatics, which is carried out, in supergravity reactor is hydrocracked 北京化工大学 2019-06-28 CN claimed
CN-109851462-A A kind of production method of ten hexahydro pyrene of medicine intermediate 中国石油化工股份有限公司 2019-06-07 CN claimed
US-8546062-B2 Self-forming top anti-reflective coating compositions and, photoresist mixtures and method of imaging using same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2013-10-01 US claimed
US-20120070782-A1 SELF-FORMING TOP ANTI-REFLECTIVE COATING COMPOSITIONS AND, PHOTORESIST MIXTURES AND METHOD OF IMAGING USING SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-22 US claimed
US-8097401-B2 Self-forming top anti-reflective coating compositions and, photoresist mixtures and method of imaging using same INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-01-17 US claimed
EP-2389359-A1 SELF-FORMING TOP ANTI-REFLECTIVE COATING COMPOSITIONS AND, PHOTORESIST MIXTURES AND METHOD OF IMAGING USING SAME International Business Machines Corporation (US) 2011-11-30 EP claimed
US-8041137-B2 Tiled output mode for image sensors BROADCOM CORPORATION (US) 2011-10-18 US claimed
US-20100244665-A1 SUBSTITUTED PYRENES AND ASSOCIATED PRODUCTION METHODS FOR LUMINESCENT APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY 2010-09-30 US claimed
WO-2010111345-A1 SELF-FORMING TOP ANTI-REFLECTIVE COATING COMPOSITIONS AND, PHOTORESIST MIXTURES AND METHOD OF IMAGING USING SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-09-30 WO claimed
US-20100248145-A1 SELF-FORMING TOP ANTI-REFLECTIVE COATING COMPOSITIONS AND, PHOTORESIST MIXTURES AND METHOD OF IMAGING USING SAME INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-09-30 US claimed
US-20080213624-A1 ORGANIC ELECTRONIC DEVICE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-04 US claimed
WO-2008106210-A1 ORGANIC ELECTRONIC DEVICE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100244665-A1 SUBSTITUTED PYRENES AND ASSOCIATED PRODUCTION METHODS FOR LUMINESCENT APPLICATIONS MYC, APC, MYCBP CYP3A4 43/4885TSHR 3473/4885ADRA2A 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.