SCHEMBL3339360

SCHEMBL3339360

CCCc1nc2c(n1Cc1ccc(-c3ccccc3C3(C(c4ccccc4)(c4ccccc4)c4ccccc4)N=NN=N3)cc1)C(=O)OC2(C)C

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.41
AGTR1 P30556 2/20 0.40
AGTR2 P50052 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9168337 0.79 PPARG (0.65) PPARGAGTR1AGTR2
SCHEMBL7308562 0.79 AGTR1 (0.47) AGTR1AGTR2
SCHEMBL7304485 0.78 AGTR1 (0.53) AGTR1
SCHEMBL8845238 0.78 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL7312391 0.77 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL1970345 0.77 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL7310118 0.76 AGTR1 (0.54) AGTR1AGTR2
Water SCHEMBL2576561 0.76 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL3342427 0.76 AGTR1 (0.60) AGTR1AGTR2
SCHEMBL7303268 0.75 AGTR1 (0.49) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076492-B2 Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil CIPLA LIMITED (IN) 2011-12-13 US disclosed
US-20100160643-A1 Process for Preparing Trityl Olmesartan Medoxomil and Olmesartan Medoxomil CIPLA LIMITED (IN) 2010-06-24 US disclosed
EP-2074116-A2 PROCESS FOR PREPARING TRITYL OLMESARTAN MEDOXOMIL AND OLMESARTAN MEDOXOMIL Cipla Limited (IN) 2009-07-01 EP disclosed
WO-2008043996-A2 PROCESS FOR PREPARING TRITYL OLMESARTAN MEDOXOMIL AND OLMESARTAN MEDOXOMIL CIPLA LIMITED (IN) 2008-04-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160643-A1 Process for Preparing Trityl Olmesartan Medoxomil and Olmesartan Medoxomil MED1, AGTR1, MED12 PPARG 1292/4885AGTR1 2/4885AGTR2 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.