Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285645 | 0.84 | PPARG (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL28399163 | 0.80 | AGTR2 (0.47) | AGTR1AGTR2 | |
| SCHEMBL3339360 | 0.79 | PPARG (0.41) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396958 | 0.79 | PPARG (1.00) | PPARGAGTR1AGTR2 | |
| SCHEMBL683751 | 0.78 | AGTR1 (0.67) | PPARGAGTR1AGTR2 | |
| SCHEMBL683762 | 0.77 | AGTR1 (0.66) | PPARGAGTR1AGTR2 | |
| SCHEMBL29833187 | 0.77 | PPARG (0.70) | PPARG | |
| SCHEMBL29833188 | 0.77 | PPARG (0.70) | PPARG | |
| SCHEMBL671 | 0.77 | PPARG (0.67) | PPARG | |
| SCHEMBL9853648 | 0.76 | PPARG (0.74) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389660-A | Hypotensive agents | MERCK & CO., INC. (US) | 1995-02-14 | — | — | US | disclosed |
| US-5164407-A | Hypotensive agents | MERCK & CO., INC. (US) | 1992-11-17 | — | — | US | disclosed |