Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343220 | 0.83 | GAA (0.48) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL4409901 | 0.77 | GAA (0.50) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL22089529 | 0.75 | GAA (0.44) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL563195 | 0.74 | GAA (0.56) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL1127304 | 0.74 | GAA (0.56) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL2074701 | 0.73 | GAA (0.54) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL10048124 | 0.73 | GAA (0.54) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL2262832 | 0.73 | GAA (0.54) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL1224654 | 0.72 | GAA (0.64) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL2593140 | 0.72 | GAA (0.64) | GAAMGAMSIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152206-A1 | Bicyclic Dihydropyrimidines and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2010-06-17 | — | — | US | disclosed |
| US-20100152206-A1 | Bicyclic Dihydropyrimidines and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152206-A1 | Bicyclic Dihydropyrimidines and Uses Thereof | KIF5A, KIF5C, KIF5B | GAA 590/4885MGAM 3539/4885SI 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.