SCHEMBL33399

SCHEMBL33399

[CH2]CCCOC(=O)C(=C)C

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.64
THRB P10828 1/20 0.55
TDP1 Q9NUW8 2/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 5/20 0.42
HPGD P15428 1/20 0.33
CYP3A4 P08684 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
ATM Q13315 1/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142371 0.93 TSHR (0.68) TSHRTHRBTDP1POLBAPEX1
SCHEMBL1228562 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL33382 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL227734 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL1142983 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL329015 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL1228461 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL33312 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL10437170 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1
SCHEMBL9357929 0.91 TSHR (0.71) TSHRTHRBTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2135 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024135982-A1 COLORED CONTACT LENSES AND MANUFACTURING METHOD THEREFOR 윤경태 2024-06-27 WO claimed
CN-115003773-B Aqueous dispersions of polymer particles and their use as adhesive compositions 阿科玛法国公司 2024-06-11 CN claimed
CN-117916248-A Transparent polymeric materials with high oxygen diffusivity comprising difunctional POSS cages with hydrophilic substituents 敏锐聚合物有限公司 2024-04-19 CN claimed
EP-3632993-B1 LOW-GLOSS CURED PRODUCT HAVING EXCELLENT STAIN RESISTANCE, AND MANUFACTURING METHOD THEREFOR LG HAUSYS LTD (KR) 2024-04-10 EP claimed
EP-4334328-A1 TRANSPARENT POLYMERIC MATERIALS WITH HIGH OXYGEN DIFFUSION CONTAINING DI-FUNCTIONAL POSS CAGES WITH HYDROPHILIC SUBSTITUENTS Acuity Polymers, Inc. (US) 2024-03-13 EP claimed
CN-117210208-B Multiple double-effect collapse-preventing environment-friendly high-performance drilling fluid and preparation method thereof 中石化西南石油工程有限公司 2024-02-27 CN claimed
CN-117210208-A Multiple double-effect collapse-preventing environment-friendly high-performance drilling fluid and preparation method thereof 中石化西南石油工程有限公司 2023-12-12 CN claimed
EP-4214247-A1 COMPOSITION COMPRISING ADDITIVE HAVING A POLYCYCLIC AROMATIC GROUP E Ink Corporation (US) 2023-07-26 EP claimed
EP-3585748-B1 OPTICAL FIBER COATING COMPOSITION NUFERN (US) 2023-07-19 EP claimed
WO-2023113779-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2023-06-22 WO claimed
US-5981682-A Silicon bonding agent for optical memory element, optical memory element, and method for manufacturing optical memory element DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-11-09 US claimed
EP-0853645-A4 AQUEOUS CURABLE SILANE/POLYMER COMPOSITIONS OSI SPECIALTIES INC (US) 1998-12-16 EP claimed
EP-0853645-A1 AQUEOUS CURABLE SILANE/POLYMER COMPOSITIONS OSi SPECIALTIES, INC. (US) 1998-07-22 EP claimed
WO-1997012940-A1 AQUEOUS CURABLE SILANE/POLYMER COMPOSITIONS OSI SPECIALTIES, INC. (US) 1997-04-10 WO claimed
EP-0509516-B1 Dental restoration composition SANKIN IND CO (JP) 1997-03-26 EP claimed
EP-0325038-B1 Surface priming composition for proteinaceous substrates, method of making and using same OPI PROD INC (US) 1993-11-03 EP claimed
EP-0539099-A2 Repositionable optical cover for monitors OPTICAL COATING LABORATORY, INC. (US) 1993-04-28 EP claimed
US-4913939-A Reaction product of cyclic anhydride and hydroxy compound; adhesion of adhesives REM SYSTEMS, INC. (US) 1990-04-03 US claimed
US-4863993-A Surface priming composition for proteinaceous substrates; method of making and using same OPI PRODUCTS, INC. (US) 1989-09-05 US claimed
EP-0325038-A2 Surface priming composition for proteinaceous substrates, method of making and using same OPI PRODUCTS, INC. (US) 1989-07-26 EP claimed