⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877351 | 0.85 | ALDH1A1 (0.44) | — | |
| SCHEMBL10973887 | 0.79 | LTA4H (0.50) | — | |
| SCHEMBL14876890 | 0.79 | TRIM24 (0.41) | — | |
| SCHEMBL3222406 | 0.76 | ALDH1A1 (0.54) | — | |
| SCHEMBL9014614 | 0.75 | TLR4 (0.49) | — | |
| SCHEMBL10546835 | 0.75 | CALM1 (0.44) | — | |
| SCHEMBL3225817 | 0.74 | CYP2A6 (0.44) | — | |
| SCHEMBL3227490 | 0.72 | HSD17B10 (0.46) | — | |
| SCHEMBL3222382 | 0.72 | APP (0.44) | — | |
| SCHEMBL3228247 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946025-A | 1-Oxygen-2, 8-diazacyclic sunflower ketone derivative and synthetic method and application thereof | 广西师范大学 | 2024-04-30 | — | — | CN | claimed |
| CN-114276288-B | Synthesis method and application of chiral alpha-propargyl-3-indole compound and derivative thereof | 中山大学 | 2023-11-03 | — | — | CN | claimed |
| CN-110117247-A | Asymmetric two sulphur class compounds and its synthetic method and application | 华东师范大学 | 2019-08-13 | — | — | CN | claimed |
| EP-2758051-B1 | CYANOMETHYLPYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-04-11 | — | — | EP | claimed |
| US-20160199355-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MAYERS SQUIBB COMPANY (US) | 2016-07-14 | — | — | US | claimed |
| US-9328099-B2 | Cyanomethylpyrazole carboxamides as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-05-03 | — | — | US | claimed |
| US-9326973-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-03 | — | — | US | claimed |
| US-8921405-B2 | Compounds | OREXO AB (SE) | 2014-12-30 | — | — | US | claimed |
| EP-2802326-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2014-11-19 | — | — | EP | claimed |
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | claimed |
| US-4826965-A | Metal complexes containing optically active sugar ligands, a process for their preparation and their use as chiral reactants for synthesis of alcohols and amines | CIBA-GEIGY CORPORATION (US) | 1989-05-02 | — | — | US | claimed |
| EP-0254685-A2 | Complexes with optically active sugar ligands, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1988-01-27 | — | — | EP | claimed |
| US-4489093-A | Insecticidal esters | ROUSSEL UCLAF (FR) | 1984-12-18 | — | — | US | claimed |
| US-4381310-A | Antimycotic substituted 2,4-dichlorophenyl-imidazolyl-vinyl-carbinols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-26 | — | — | US | claimed |
| EP-0010297-B1 | DERIVATIVES OF POLYENE MACROLIDE ANTIBIOTICS CONTAINING AN AMINO SUGAR MOIETY, PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-04-13 | — | — | EP | claimed |
| EP-0048828-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl carbinols, process for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| US-4272525-A | FUNGICIDES | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | claimed |
| EP-0010297-A1 | Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-04-30 | — | — | EP | claimed |
| US-4196151-A | Process for producing β,γ-unsaturated aldehyde | NIPPON OIL AND FATS CO., LTD. (JP) | 1980-04-01 | — | — | US | claimed |