Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225817 | 0.76 | CYP2A6 (0.44) | LMNACYP2A6MAOB | |
| SCHEMBL28891781 | 0.74 | APP (0.37) | — | |
| SCHEMBL3230155 | 0.74 | CYP2A6 (0.46) | CYP2A6MAOBFBP1GRIN2DGRIN3B | |
| SCHEMBL3981306 | 0.74 | HSD17B10 (0.46) | HSD17B10LMNACYP2A6MAOBAHR | |
| SCHEMBL3221866 | 0.74 | TSHR (0.42) | AHR | |
| SCHEMBL3222382 | 0.74 | APP (0.44) | HSD17B10MAOB | |
| SCHEMBL3228392 | 0.74 | ALDH5A1 (0.46) | HSD17B10LMNAMAOBCYP1A2HDAC6 | |
| SCHEMBL3227313 | 0.74 | NFE2L2 (0.42) | MAOBFBP1 | |
| SCHEMBL3232289 | 0.73 | ALDH1A1 (0.52) | HSD17B10AHR | |
| SCHEMBL334039 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998454-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2003-03-26 | — | — | EP | claimed |
| US-6271262-B1 | AMIDESULFONAMIDE COMPOUNDS AS ENZYME INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-08-07 | — | — | US | claimed |
| EP-0998454-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-05-10 | — | — | EP | claimed |
| WO-1999003826-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-01-28 | — | — | WO | claimed |
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| CN-101568258-A | Pyridine derivatives for combating pests | BASF SE (DE) | 2009-10-28 | — | — | CN | disclosed |
| EP-0998454-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2003-03-26 | — | — | EP | disclosed |
| US-6358987-B1 | FOR THERAPY AND PROPHYLAXIS OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL EPIDERMAL OR GASTRIC ULCERATION, AND TUMOUR METASTASIS, INVASION AND GROWTH | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-03-19 | — | — | US | disclosed |
| US-6271262-B1 | AMIDESULFONAMIDE COMPOUNDS AS ENZYME INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-08-07 | — | — | US | disclosed |
| EP-0998454-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999003826-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | HSD17B10 3403/4885LMNA 3402/4885CYP2A6 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.