SCHEMBL3341600

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4082792	0.83	TDP1 (0.33)	TDP1MAPK1KIF11LMNATSHR
	SCHEMBL5928060	0.77	TSHR (0.39)	MAPK1KIF11LMNATSHRALDH1A1
	SCHEMBL5614716	0.77	KCNN4 (0.40)	MAPK1KIF11LMNATSHRALDH1A1
	SCHEMBL10830860	0.75	TDP1 (0.42)	TDP1MAPK1KIF11TSHRALDH1A1
	SCHEMBL28287845	0.73	KIF11 (0.54)	TDP1KIF11TSHRALDH1A1KCNN4
	SCHEMBL8048324	0.73	MAPK1 (0.39)	MAPK1KIF11LMNATSHRALDH1A1
	SCHEMBL7764290	0.71	KCNN4 (0.43)	MAPK1KIF11LMNATSHRALDH1A1
	Phosphine SCHEMBL28245164	0.71	KIF11 (0.52)	TDP1KIF11TSHRALDH1A1KCNN4
	SCHEMBL6529293	0.71	CYP2C19 (0.43)	LMNAALDH1A1TAAR1ALOX15CYP1A2
	SCHEMBL7785965	0.71	SIGMAR1 (0.40)	MAPK1SIGMAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.