Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | FADS1 | O60427 | 2/20 | 0.51 |
| ▸ | PRKCI | P41743 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815342 | 0.86 | FADS1 (0.56) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL10428747 | 0.86 | KMT2A (0.60) | MEN1KMT2ALMNAKLKB1TDP1 | |
| SCHEMBL9173879 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL11505052 | 0.85 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9172162 | 0.84 | JAK2 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL10428749 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KMT2AFADS1PTGS1 | |
| SCHEMBL3327224 | 0.83 | TMPRSS4 (0.65) | ALDH1A1MEN1KMT2AKDM4EFADS1 | |
| SCHEMBL22720135 | 0.83 | HSPD1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11761604 | 0.83 | NPC1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2957280 | 0.83 | MEN1 (0.61) | ALDH1A1SMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |