Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005339 | 0.78 | TRPM8 (0.46) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL247809 | 0.76 | KDM4E (0.38) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL28449626 | 0.76 | L3MBTL1 (0.42) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL17220649 | 0.75 | ALDH1A1 (0.40) | KMT2AMEN1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL16968516 | 0.75 | TACR1 (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1HDAC4 | |
| SCHEMBL1427899 | 0.74 | KMT2A (0.40) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL1208112 | 0.74 | MEN1 (0.37) | KMT2AMEN1HTTL3MBTL1RIPK1 | |
| SCHEMBL5655590 | 0.74 | CA12 (0.43) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL7034982 | 0.72 | KMT2A (0.47) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL20564934 | 0.72 | KMT2A (0.36) | KMT2AMEN1HTTL3MBTL1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |