Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629328 | 0.90 | CA2 (0.48) | CA2PLA2G2CAKR1B1HDAC11FFAR4 | |
| SCHEMBL6830568 | 0.84 | FFAR4 (0.52) | AKR1B1HDAC11FFAR4FFAR1GPR84 | |
| SCHEMBL8984375 | 0.83 | FFAR4 (0.50) | CA2PLA2G2CHDAC11FFAR4FFAR1 | |
| SCHEMBL3930979 | 0.83 | CAMK2A (0.44) | CA2AKR1B1HDAC11HDAC3HDAC1 | |
| SCHEMBL4875928 | 0.82 | CA2 (0.55) | CA2PLA2G2CAKR1B1HDAC11HDAC3 | |
| SCHEMBL5077959 | 0.81 | FFAR4 (0.53) | PLA2G2CAKR1B1HDAC11FFAR4FFAR1 | |
| Trifluoroacetic Acid SCHEMBL720969 | 0.80 | ACE2 (0.46) | CA2FAAHMAPTALDH1A1MEN1 | |
| SCHEMBL5082422 | 0.80 | FFAR4 (0.55) | AKR1B1HDAC11FFAR4FFAR1GPR84 | |
| SCHEMBL6720816 | 0.79 | CA2 (0.52) | CA2PLA2G2CAKR1B1HDAC11FFAR4 | |
| SCHEMBL28184368 | 0.79 | FFAR4 (0.57) | CA2PLA2G2CAKR1B1HDAC11FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172443-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE | HAMARI CHEMICALS LTD (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8222452-B2 | Method for producing optically active amines | HAMARI CHEMICALS, LTD. (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100160636-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | HAMARI CHEMICALS, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2172443-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE | Hamari Chemicals, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160636-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | INMT, HNMT, PADI3 | CA2 3190/4885PLA2G2C 2845/4885AKR1B1 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.