Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nialamide SCHEMBL49430 | 0.83 | CA1 (0.62) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4071835 | 0.83 | CYP1A2 (0.73) | GAAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4075670 | 0.83 | CYP1A2 (0.73) | GAAALDH1A1MAPTSMN1; SMN2MEN1 | |
| Nialamide SCHEMBL7324704 | 0.82 | CA1 (0.61) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16610101 | 0.81 | GAA (0.66) | GAAALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL11613978 | 0.80 | ALDH1A1 (1.00) | GAAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL16353747 | 0.78 | HTT (0.65) | GAAALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL2695730 | 0.78 | ALDH1A1 (0.58) | GAAALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL3363032 | 0.76 | ALDH1A1 (0.46) | GAAALDH1A1MAPTSMN1; SMN2HTT | |
| Nialamide SCHEMBL28086228 | 0.76 | RAB9A (0.55) | GAAALDH1A1MAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |