Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412830 | 0.77 | LOXL2 (0.50) | ALDH1A1HSD17B10SMN1; SMN2GAAMAPT | |
| SCHEMBL3342974 | 0.76 | GAA (0.66) | ALDH1A1SMN1; SMN2GAAMAPTHTT | |
| SCHEMBL6929919 | 0.76 | RECQL (0.62) | ALDH1A1HSD17B10SMN1; SMN2GAAMAPT | |
| SCHEMBL31269854 | 0.76 | ALDH1A1 (0.50) | ALDH1A1 | |
| Iodide SCHEMBL20524285 | 0.74 | RECQL (0.61) | ALDH1A1HSD17B10SMN1; SMN2GAAMAPT | |
| SCHEMBL28113107 | 0.74 | GAA (0.49) | GAAATMCA2 | |
| SCHEMBL660683 | 0.74 | LOXL2 (0.52) | ALDH1A1LMNA | |
| SCHEMBL1812215 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HSD17B10GAAMAPTHTT | |
| SCHEMBL6468844 | 0.72 | LMNA (0.45) | ALDH1A1SMN1; SMN2MAPTHTTRAB9A | |
| SCHEMBL1286084 | 0.72 | HRH1 (0.53) | ALDH1A1SMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |