Chlorobenzene

Chlorobenzene

SCHEMBL3343166

ClCC(Cl)CCl.Clc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.58
CYP1A2 P05177 1/20 0.42
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
IDO1 P14902 2/20 0.35
TDO2 P48775 2/20 0.35
SIGMAR1 Q99720 1/20 0.35
LMNA P02545 2/20 0.35
CYP2A6 P11509 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
ORAI1 Q96D31 1/20 0.34
ORAI2 Q96SN7 1/20 0.34
ORAI3 Q9BRQ5 1/20 0.34
TRPV6 Q9H1D0 1/20 0.34
SCN4A P35499 2/20 0.34
CHRNA7 P36544 1/20 0.34
HIF1A Q16665 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
MAPK1 P28482 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL10971193 0.86 TSHR (0.61) TSHRCYP1A2KDM4EGAAIDO1
Chlorobenzene SCHEMBL947510 0.80 TSHR (0.79) TSHRCYP1A2KDM4EGAAIDO1
Chlorobenzene SCHEMBL149324 0.80 TSHR (0.79) TSHRCYP1A2KDM4EGAAIDO1
1,2,3-Trichloropropane SCHEMBL28546324 0.80 TSHR (0.47) TSHRTDP1TP53
Chlorobenzene SCHEMBL11653316 0.79 TSHR (0.58) TSHRCYP1A2KDM4EGAAIDO1
Chlorobenzene SCHEMBL5038205 0.77 TSHR (0.73) TSHRCYP1A2KDM4EGAAIDO1
Chlorobenzene SCHEMBL8991467 0.77 TSHR (0.73) TSHRCYP1A2KDM4EGAAIDO1
SCHEMBL24715429 0.76 TSHR (1.00) TSHRCYP1A2KDM4EGAAIDO1
Chlorobenzene SCHEMBL2168046 0.76 TSHR (1.00) TSHRCYP1A2KDM4EGAAIDO1
Chlorobenzene SCHEMBL2044 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100159539-A1 METHODS AND SYSTEMS FOR PRODUCING BIOFUELS AND BIOENERGY PRODUCTS FROM XENOBIOTIC COMPOUNDS ASCON MIGUEL 2010-06-24 US disclosed