Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665092 | 0.84 | CA2 (0.42) | LSSCARM1PRMT6DAGLBKCNH2 | |
| SCHEMBL15093755 | 0.81 | NAAA (0.40) | CARM1PRMT6HRH3CA2CA9 | |
| SCHEMBL3342643 | 0.80 | GPR119 (0.57) | GPR119 | |
| SCHEMBL22458967 | 0.77 | GPR119 (0.46) | GPR119TP53DRD2 | |
| SCHEMBL3344962 | 0.75 | GPR119 (0.41) | GPR119DRD2KCNH2 | |
| SCHEMBL16936796 | 0.75 | LSS (0.40) | LSSDRD2KCNH2 | |
| SCHEMBL16879289 | 0.73 | ESR2 (0.55) | — | |
| SCHEMBL4952656 | 0.72 | CA2 (0.58) | CA2CA9 | |
| SCHEMBL18707815 | 0.71 | SLC18A3 (0.50) | TP53DRD2KCNH2 | |
| SCHEMBL15771678 | 0.71 | CA2 (0.43) | DAGLBCA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |